ArticleInfection control and hospital epidemiology2017
Intervention to Reduce Broad-Spectrum Antibiotics and Treatment Durations Prescribed at the Time of Hospital Discharge: A Novel Stewardship Approach.
Article in Infection control and hospital epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05826873 (Implementing a Discharge Stewardship Bundle to Improve Antibiotic Use at Transition From Hospital to Home), which is not on this map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementing a Discharge Stewardship Bundle to Improve Antibiotic Use at Transition From Hospital to Home
Who cites it
34 citing papers in PubMed.
- Prospective Audit and Feedback by Antibiotic Stewardship Teams to Reduce Antibiotic Overuse at Hospital Discharge: A Stepped-Wedge Cluster-Randomized Clinical Trial.JAMA network open · 2026Trial
- Reducing overuse of antibiotics at discharge home: A single-center mixed methods pilot study.American journal of infection control · 2022Trial
- Qualitative assessment of antibiotic stewardship teams' efforts to perform prospective audit-and-feedback at hospital discharge.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Impact of a post-prescription audit and feedback antimicrobial stewardship intervention on inappropriate carbapenem prescribing: an interrupted time series analysis.JAC-antimicrobial resistance · 2025Article
- Association between postdischarge antibiotic use andAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Implementing with intention: advantages, challenges, and tactics to optimally utilize the AXR metric.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Optimizing oral antibiotic prescribing at hospital discharge: a single center, quasi-experiment pilot study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Antimicrobial stewardship initiative on prescribing at discharge from a community medical center.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Lessons from an 11-year retrospective cohort study ofIranian journal of microbiology · 2024Article
- A Novel Risk-Adjusted Metric to Compare Hospitals on Their Antibiotic Prescribing at Hospital Discharge.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Excellence in Antibiotic Stewardship: A Mixed-Methods Study Comparing High-, Medium-, and Low-Performing Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Protocol for a parallel cluster randomized trial of a participatory tailored approach to reduce overuse of antibiotics at hospital discharge: the ROAD home trial.Implementation science : IS · 2024Article
- Impact of a Medication Reconciliation Pharmacist Program on Appropriateness of Community-Acquired Pneumonia Treatment Durations at Hospital Discharge.Hospital pharmacy · 2023Article
- Optimizing transitions of care antimicrobial prescribing at a community teaching hospital.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Behavior-change interventions to improve antimicrobial stewardship in human health, animal health, and livestock agriculture: A systematic review.PLOS global public health · 2023Article
- A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in Non-Hospital Care Settings in 2021.Open forum infectious diseases · 2022Review
- Antibiotic Stewardship Strategies and Their Association With Antibiotic Overuse After Hospital Discharge: An Analysis of the Reducing Overuse of Antibiotics at Discharge (Road) Home Framework.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- A Statewide Collaborative Quality Initiative to Improve Antibiotic Duration and Outcomes in Patients Hospitalized With Uncomplicated Community-Acquired Pneumonia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Detecting inappropriate total duration of antimicrobial therapy using semi-automated surveillance.Antimicrobial resistance and infection control · 2022Article
- Antimicrobial Stewardship at Transitions of Care to Outpatient Settings: Synopsis and Strategies.Antibiotics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
OBJECTIVE For most common infections requiring hospitalization, antibiotic treatment is completed after hospital discharge. Postdischarge therapy is often unnecessarily broad spectrum and prolonged. We developed an intervention to improve antibiotic selection and shorten treatment durations. DESIGN Single center, quasi-experimental retrospective cohort study METHODS Patients prescribed oral antibiotics at hospital discharge before (July 2012-June 2013) and after (October 2014-February 2015) an intervention consisting of (1) institutional guidance for oral step-down antibiotic selection and duration of therapy and (2) pharmacy audit of discharge prescriptions with real-time prescribing recommendations to providers. The primary outcomes measured were total prescribed duration of therapy and use of antibiotics with broad gram-negative activity (ie, fluoroquinolones or amoxicillin-clavulanate). RESULTS Overall, 300 cases from the preintervention period and 200 cases from the intervention period were included. Compared with the preintervention period, the use of antibiotics with broad gram-negative activity decreased during the intervention (51% vs 40%; P=.02), particularly fluoroquinolones (38% vs 25%; P=.002). The total duration of therapy decreased from a median of 10 days (interquartile range [IQR], 7-13 days) to 9 days (IQR, 6-13 days) but did not reach statistical significance (P=.13). However, the duration prescribed at discharge declined from 6 days (IQR, 4-10 days) to 5 days (IQR, 3-7 days) (P=.003). During the intervention, there was a nonsignificant increase in the overall appropriateness of discharge prescriptions from 52% to 66% (P=.15). CONCLUSIONS A multifaceted intervention to optimize antibiotic prescribing at hospital discharge was associated with less frequent use of antibiotics with broad gram-negative activity and shorter postdischarge treatment durations. Infect Control Hosp Epidemiol 2017;38:534-541.
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