ArticleEpidemiology and infection2017
Characterisation of invasive clinical Haemophilus influenzae isolates in Queensland, Australia using whole-genome sequencing.
Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- InvasiveDiseases (Basel, Switzerland) · 2026Article
- Whole-genome sequencing of non-typeable Haemophilus influenzae isolated from a tertiary care hospital in Surabaya, Indonesia.BMC infectious diseases · 2024Article
- Examination of phase-variable haemoglobin-haptoglobin binding proteins in non-typeable Haemophilus influenzae reveals a diverse distribution of multiple variants.FEMS microbiology letters · 2022Article
- Characterization of the Phase-Variable Autotransporter Lav Reveals a Role in Host Cell Adherence and Biofilm Formation in Nontypeable Haemophilus influenzae.Infection and immunity · 2022Article
- Comparative pangenome analysis of capsulated Haemophilus influenzae serotype f highlights their high genomic stability.Scientific reports · 2022Article
- Epidemiology and population structure ofMicrobial genomics · 2021Article
- Learning from -omics strategies applied to uncoverComputational and structural biotechnology journal · 2021Review
- Epidemiology of Haemophilus influenzae in the Republic of Ireland, 2010-2018.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Widespread of non-typeable Haemophilus influenzae with high genetic diversity after two decades use of Hib vaccine in China.Journal of clinical laboratory analysis · 2020Article
- Emergence of a clone of invasiveJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2020Article
- Genomic characterization of Haemophilus influenzae: a focus on the capsule locus.BMC genomics · 2019Article
- hicap:Journal of clinical microbiology · 2019Article
- Analysis of Invasive NontypeableInfection and immunity · 2019Article
- Article
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Abstract
Haemophilus influenzae is an important aetiological organism of both adult and child respiratory disease. The number of non-typeable (NTHi) invasive H. influenzae isolates referred to the Queensland (QLD) Public Health Microbiology laboratory has increased notably year-by-year. In this study we used whole-genome sequencing to molecularly characterise 100 referred invasive H. influenzae, including 74 NTHi isolates over a 15-year period, observing the carriage of capsular and putative virulence genes, including the major adhesins, antimicrobial resistance genes and population diversity. Encapsulated isolates were largely clonal, however NTHi isolates displayed high genetic variability by MLST and single nucleotide polymorphism typing with no dominant clone observed. The only mechanism for β-lactam resistance identified in the QLD isolates was β-lactamase production. No single set of virulence determinants was conclusively associated with invasive QLD NTHi isolates.
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