Evidence map›Paper›PMID 28260526›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2017

Comparison of CT and CMR for detection and quantification of carotid artery calcification: the Rotterdam Study.

Blerim Mujaj, Andrés M Arias Lorza, Arna van Engelen, Marleen de Bruijne, Oscar H Franco, Aad van der Lugt, Meike W Vernooij, Daniel Bos

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Journal of Cardiovascular Magnetic Resonance: 2017/2018 in review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2019
    Review
  7. Article
  8. Journal of Cardiovascular Magnetic Resonance 2017.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2018
    Review
  9. Article
  10. Imaging Cardiovascular Calcification.Journal of the American Heart Association · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Blerim MujajDepartment of Epidemiology, Erasmus MC, University Medical Center, Office Na 2824k, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Andrés M Arias LorzaBiomedical Imaging Group Rotterdam, Departments of Medical Informatics, Radiology, and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Arna van EngelenBiomedical Imaging Group Rotterdam, Departments of Medical Informatics, Radiology, and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Marleen de BruijneBiomedical Imaging Group Rotterdam, Departments of Medical Informatics, Radiology, and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Oscar H FrancoDepartment of Epidemiology, Erasmus MC, University Medical Center, Office Na 2824k, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Aad van der LugtDepartment of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Meike W VernooijDepartment of Epidemiology, Erasmus MC, University Medical Center, Office Na 2824k, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Daniel BosDepartment of Epidemiology, Erasmus MC, University Medical Center, Office Na 2824k, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. d.bos@erasmusmc.nl.
Erasmus MC · NLHarvard University · USUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarotid artery atherosclerosis is an important risk factor for stroke. As such, quantitative imaging of carotid artery calcification, as a proxy of atherosclerosis, has become a cornerstone of current stroke research. Yet, population-based data comparing the computed tomography (CT) and cardiovascular magnetic resonance (CMR) for the detection and quantification of calcification remain scarce.

methodsA total of 684 participants from the population-based Rotterdam Study underwent both a CT and CMR of the carotid artery bifurcation to quantify the amount of carotid artery calcification (mean interscan interval: 4.9 ± 1.2 years). We investigated the correlation between the amount of calcification measured on CT and CMR using Spearman's correlation coefficient, Bland-Altman plots, and linear regression. In addition, using logistic regression modeling, we assessed the association of CT and CMR based calcification volumes with a history of stroke.

resultsWe found a strong correlation between CT and CMR based calcification volumes (Spearman's correlation coefficient:0.86, p-value ≤0.01). Bland-Altman analyses showed a good agreement, though CT based calcification volumes were systematically larger. Finally, calcification volume assessed with either imaging modality was associated with a history of stroke with similar effect estimates (odds ratio (OR) per 1-SD increase in calcification volume: 1.52 (95% CI:1.00;2.30) for CT, and 1.47 (95% CI:1.01;2.14) for CMR.

conclusionCT based and CMR based volumes of carotid artery calcification are highly correlated, but CMR based calcification is systematically smaller than those obtained with CT. Despite this difference, both provide comparable information with regard to a history of stroke.

Indexed as

Computed Tomography AngiographyMagnetic Resonance AngiographyMultidetector Computed TomographyAgedCarotid Artery DiseasesFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNetherlandsOdds RatioPredictive Value of TestsPrognosisProspective StudiesAtherosclerosisCalcificationCarotid arteryCMRCTStroke

Identifiers

PMID28260526
PMCPMC5338077
OpenAlexW2590205493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.