ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017
Perilesional edema in brain metastasis from non-small cell lung cancer (NSCLC) as predictor of response to radiosurgery (SRS).
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 33 citations in OpenAlex.
- Brain metastases from ovarian cancer: neuroradiological profile and survival overview of neurosurgical cases.Journal of neuro-oncology · 2025Observational
- Imaging Characteristics and Clinical Outcomes in Gastric Cancer with Brain Metastasis: A Propensity Score-Matched Study.Journal of gastrointestinal cancer · 2025Article
- Article
- Predictive value of perilesional edema volume in melanoma brain metastasis response to stereotactic radiosurgery.Journal of neuro-oncology · 2024Article
- Growth speed of large brain metastases between diagnostic and radiosurgical planning MRI and predictors of rapid tumor growth.Japanese journal of radiology · 2024Article
- Evaluation of brain metastasis edema in breast cancer patients as a marker for Ki-67 and cell count-A single center analysis.The neuroradiology journal · 2024Article
- Enhancing intracranial efficacy prediction of osimertinib in non-small cell lung cancer: a novel approach through brain MRI radiomics.Frontiers in neurology · 2024Article
- Automated identification and quantification of metastatic brain tumors and perilesional edema based on a deep learning neural network.Journal of neuro-oncology · 2024Article
- Prognostic analysis of stereotactic radiosurgery for brain metastases: a single-center retrospective study.La Radiologia medica · 2023Article
- AI Evaluation of Imaging Factors in the Evolution of Stage-Treated Metastases Using Gamma Knife.Diagnostics (Basel, Switzerland) · 2023Article
- The emerging potential of quantitative MRI biomarkers for the early prediction of brain metastasis response after stereotactic radiosurgery: a scoping review.Quantitative imaging in medicine and surgery · 2023Article
- Perilesional edema diameter associated with brain metastases as a predictive factor of response to radiotherapy in non-small cell lung cancer.Frontiers in oncology · 2023Article
- Laser interstitial thermal therapy for newly diagnosed glioblastoma.Lasers in medical science · 2022Article
- Machine Learning-Based Radiomics in Neuro-Oncology.Acta neurochirurgica. Supplement · 2022Review
- Perilesional edema in brain metastases as predictive factor of response to systemic therapy in non-small cell lung cancer patients: a preliminary study.Annals of translational medicine · 2021Article
- Multi-parametric qualitative and quantitative MRI assessment as predictor of histological grading in previously treated meningiomas.Neuroradiology · 2020Article
- The Effect of Epidermal Growth Factor Receptor Mutation on Intracranial Progression-Free Survival of Non-Small Cell Lung Cancer Patients with Brain Metastasis Underwent Gamma Knife Radiosurgery.Brain tumor research and treatment · 2020Article
- Applications of radiomics and machine learning for radiotherapy of malignant brain tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Review
- Single-fraction radiosurgery versus fractionated stereotactic radiotherapy in patients with brain metastases: a comparative study.Clinical & experimental metastasis · 2020Article
- Role of perilesional edema and tumor volume in the prognosis of non-small cell lung cancer (NSCLC) undergoing radiosurgery (SRS) for brain metastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019Article
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12 authors at 1 institution in 1 country.
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Abstract
Radiosurgery (SRS) is widely used in the treatment of brain oligo-metastases from NSCLC. The aim of present study is to evaluate the extent of perilesional edema in brain metastases as predictive factor of treatment response. This single center retrospective study included 42 consecutive patients (January 2011-December 2014) with 1-2 brain metastasis from NSCLC treated with Radiosurgery (SRS). Extent of perilesional edema was measured as maximal extension from the edge of lesion and classified as minor (<10 mm) or major (≥10 mm). We analyzed Modality of Brain Recurrence (MBR), classified as in-field or out-of- field, and Brain Progression Free-Survival (BPFS) after treatment stratified according to extent of perilesional edema. Analyzing modality of brain recurrence and BPFS, after a median follow-up of 6 months, we found that patients with minor edema had a better radiological response to SRS with none in-field recurrences and a lower risk of the onset of new brain lesions (out-of-field recurrence). Instead, patients group with major edema had a worse response rate of lesions treated, further, a higher risk of out-of-field brain relapse. Extent of perilesional edema in brain metastasis from NSCLC could be a predictive factor of response and brain progression after SRS treatment alone.
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