SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2017
Utility scores for different health states related to depression: individual participant data analysis.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cost effectiveness of guided Internet-based interventions for depression in comparison with control conditions: An individual-participant data meta-analysis.Depression and anxiety · 2018Pooled it
- Five-year cost-effectiveness analysis of the European Fans in Training (EuroFIT) physical activity intervention for men versus no intervention.The international journal of behavioral nutrition and physical activity · 2020Trial
- Trial
- Cost-Effectiveness of a Universal School-Based Mental Health Prevention Program: An Economic Modeling Study in a Limited Income Context.Applied health economics and health policy · 2025Article
- A decision-analytic method to evaluate the cost-effectiveness of remote monitoring technology for chronic depression.International journal of technology assessment in health care · 2025Article
- Observational
- Quality of life impacts associated with comorbid insomnia and depression in adult population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Cost-effectiveness analysis of mHealth applications for depression in Germany using a Markov cohort simulation.NPJ digital medicine · 2024Article
- The Hidden Toll of Psychological Distress in Australian Adults and Its Impact on Health-Related Quality of Life Measured as Health State Utilities.Applied health economics and health policy · 2024Article
- A Canadian Simulation Model for Major Depressive Disorder: Study Protocol.PharmacoEconomics - open · 2024Review
- Value-based pricing of cognitive behavioral therapy for depression in primary care: an economic evaluation.BMC health services research · 2024Article
- Cost-effectiveness of pharmacogenomic-guided treatment for major depression.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
- To what extent does the use of crosswalks instead of EQ-5D value sets impact reimbursement decisions?: a simulation study.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Article
- Article
- Is vitamin D supplementation program in Iranian schools effective in reducing adolescent depressive symptoms? Cost effectiveness study.BMC public health · 2023Article
- Cost-Effectiveness of Acthar Gel versus Standard of Care for the Treatment of Advanced Symptomatic Sarcoidosis.ClinicoEconomics and outcomes research : CEOR · 2023Article
- Cost-utility analysis of teriflunomide in naïve vs. previously treated patients with relapsing-remitting multiple sclerosis in Italy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Health Related Quality of Life in Major Depressive Disorder: evolution in time and factors associated.Actas espanolas de psiquiatria · 2022Article
- Guided Internet-Based Cognitive Behavioral Therapy for Depression: Implementation Cost-Effectiveness Study.Journal of medical Internet research · 2021Article
- College Campuses and COVID-19 Mitigation: Clinical and Economic Value.Annals of internal medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDepression is associated with considerable impairments in health-related quality-of-life. However, the relationship between different health states related to depression severity and utility scores is unclear. The aim of this study was to evaluate whether utility scores are different for various health states related to depression severity.
methodsWe gathered individual participant data from ten randomized controlled trials evaluating depression treatments. The UK EQ-5D and SF-6D tariffs were used to generate utility scores. We defined five health states that were proposed from American Psychiatric Association and National Institute for Clinical Excellence guidelines: remission, minor depression, mild depression, moderate depression, and severe depression. We performed multilevel linear regression analysis.
resultsWe included 1629 participants in the analyses. The average EQ-5D utility scores for the five health states were 0.70 (95% CI 0.67-0.73) for remission, 0.62 (95% CI 0.58-0.65) for minor depression, 0.57 (95% CI 0.54-0.61) for mild depression, 0.52 (95%CI 0.49-0.56) for moderate depression, and 0.39 (95% CI 0.35-0.43) for severe depression. In comparison with the EQ-5D, the utility scores based on the SF-6D were similar for remission (EQ-5D = 0.70 vs. SF-6D = 0.69), but higher for severe depression (EQ-5D = 0.39 vs. SF-6D = 0.55).
conclusionsWe observed statistically significant differences in utility scores between depression health states. Individuals with less severe depressive symptoms had on average statistically significant higher utility scores than individuals suffering from more severe depressive symptomatology. In the present study, EQ-5D had a larger range of values as compared to SF-6D.
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