Evidence map›Paper›PMID 28259851›Full record

ArticleBMJ open2017

Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI).

Conny Tanjung, Peter Rzehak, Muchtaruddin Mansyur, Zakiudin Munasir, Herawati Sudoyo, Suzanna Immanuel, Roedi Irawan, Eva Reischl, Hans Demmelmair, Berthold Koletzko and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Conny TanjungPostgraduate Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Peter RzehakDivision of Metabolic and Nutritional Medicine, Ludwig-Maximilians-Universität München, Dr von Hauner Children's Hospital, University of Munich Medical Centre, Munich, Germany.
Muchtaruddin MansyurFaculty of Community Medicine, Universitas Indonesia, Jakarta, Indonesia.
Zakiudin MunasirDepartment of Paediatrics, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia.
Herawati SudoyoFaculty of Medicine, Sydney University, Sydney, Australia.
Suzanna ImmanuelDepartment of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia.
Roedi IrawanDepartment of Paediatrics, Faculty of Medicine, Universitas Airlangga, Dr Sutomo General Hospital, Surabaya, Indonesia.
Eva ReischlResearch Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum Muenchen, Munich, Germany.
Hans DemmelmairDivision of Metabolic and Nutritional Medicine, Ludwig-Maximilians-Universität München, Dr von Hauner Children's Hospital, University of Munich Medical Centre, Munich, Germany.
Berthold KoletzkoDivision of Metabolic and Nutritional Medicine, Ludwig-Maximilians-Universität München, Dr von Hauner Children's Hospital, University of Munich Medical Centre, Munich, Germany.
Sri Rezeki HadinegoroDepartment of Paediatrics, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia.
Damayanti Rusli SjarifDepartment of Paediatrics, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo National Referral Hospital, Jakarta, Indonesia.
Ludwig-Maximilians-Universität München · DERumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo · IDUniversity of Indonesia · IDAirlangga University · IDHelmholtz Zentrum München · DEUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtopic dermatitis (AD) is the most common skin disorder in young children worldwide, with a high impact on morbidity and quality of life. To date, no prospective study has been published on the incidence and potential predictors of AD in South East Asian populations. The Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI) will address the genetic, metabolic and dietary characteristics of mothers and their offspring, as well as potential determinants of AD within the first year of infant life. METHODS AND ANALYSIS: This prospective study will be undertaken in about 400 infants to investigate the direct and indirect effects of filaggrin ( ETHICS AND DISSEMINATION: The Permanent Medical Research Ethics Committee in Medicine and Health/Faculty of Medicine Universitas Indonesia/Dr Cipto Mangunkusumo Hospital (No. 47/H2.F1/ETIK/2014) approved the study protocol (extended by the letter no. 148/UN2.F1/ETIK/2015). We aim to disseminate our findings via publication in an international journal with high impact factor.

Indexed as

Research DesignCohort StudiesCross-Sectional StudiesDelta-5 Fatty Acid DesaturaseDermatitis, AtopicEnvironmental ExposureFemaleFilaggrin ProteinsGenetic Predisposition to DiseaseHumansIndonesiaInfantLongitudinal StudiesMaleProspective StudiesRisk FactorsDelta-5 Fatty Acid DesaturaseFilaggrin ProteinsAtopic dermatitisFADS gene polymorphismFilaggrin gene mutationLong chain poly unsaturated fatty acid composition

Identifiers

PMID28259851
PMCPMC5353254
OpenAlexW2592677242

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.