Evidence map›Paper›PMID 28259057›Full record

Trial reportJournal of critical care2017

The accuracy of the bedside swallowing evaluation for detecting aspiration in survivors of acute respiratory failure.

Ylinne T Lynch, Brendan J Clark, Madison Macht, S David White, Heather Taylor, Tim Wimbish, Marc Moss

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in Journal of critical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02363686 nacompletednot on this map

Aspiration in Acute Respiratory Failure Survivors

TypeinterventionalSponsorUniversity of Colorado, DenverRan2012 to 2020Enrolled248ConditionsDysphagiaArmsFEES, BSE
NCT05108896 narecruitingnot on this mapstarted 2021, after this paper: background citation

Aspiration in Acute Respiratory Failure Survivors

TypeinterventionalSponsorUniversity of Colorado, DenverRan2021 to 2025Enrolled855ConditionsDysphagia, AspirationArms3-Screenings Protocol, FEES, Tracheal Ultrasound
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  6. Article
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  10. Identifying the association between post-extubation laryngeal edema and aspiration in acute respiratory failure patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
  11. Review
  12. Bedside diagnosis of silent aspiration using mobile dynamic digital radiography: a preliminary study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ylinne T LynchDivision of Pulmonary and Critical Care, University of Washington, Seattle, WA.
Brendan J ClarkDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO.
Madison MachtCritical Care, Pulmonary, and Sleep Associates, Lakewood, CO.
S David WhiteRehabilitation Therapy, University of Colorado Hospital, Aurora, CO.
Heather TaylorRehabilitation Therapy, University of Colorado Hospital, Aurora, CO.
Tim WimbishRehabilitation Therapy, University of Colorado Hospital, Aurora, CO.
Marc MossDivision of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO. Electronic address: marc.moss@ucdenver.edu.
University of Colorado Denver · USUniversity of Colorado Hospital · USUniversity of Washington · US

Funding

Patient Oriented Research Program in ALI/ARFK24HL089223 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MOSS, MARC · 2007 to 2016
$1.4M
Tailored Screening, Brief Intervention, and Referral to Treatment for Medical IntK23AA021814 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI CLARK, BRENDAN JAMES · 2014 to 2017
$688k
Aspiration in Acute Respiratory Failure SurvivorsR21NR015886 · NINR · UNIVERSITY OF COLORADO DENVER · PI MOSS, MARC · 2015 to 2016
$469k
NHLBI NIH HHS K24 HL089223NIAAA NIH HHS K23 AA021814NINR NIH HHS R21 NR015886
6 · The paper itself

Abstract

backgroundDysphagia with subsequent aspiration occurs in up to 60% of acute respiratory failure (ARF) survivors. Accurate bedside tests for aspiration can reduce aspiration-related complications while minimizing delay of oral nutrition. In a cohort of ARF survivors, we determined the accuracy of the bedside swallowing evaluation (BSE) and its components for detecting aspiration.

methodsPatients who were extubated after at least 24hours of mechanical ventilation were eligible for enrollment. Within 3 days of extubation, patients underwent comprehensive BSE including 3-oz water swallowing test (3-WST), followed by a criterion standard test for aspiration, flexible endoscopic evaluation of swallowing (FEES).

resultsForty-five patients were included in the analysis. Median patient age was 55years (interquartile range, 47-65). Median duration of mechanical ventilation was 3.3days (interquartile range 1.8-6.0). Fourteen patients (31%) aspirated on FEES. Physical examination findings on BSE and abnormal swallowing during trials of different consistencies were variably associated with aspiration. Compared with FEES, the 3-WST yielded a sensitivity of 77% (95% confidence interval [CI], 50%-92%), specificity of 65% (95% CI, 47%-79%), and an area under the receiver operating characteristic curve (AUC) of 0.71; a speech language pathologist's recommendation for altered diet yielded a sensitivity of 86% (95% CI, 60%-96%), a specificity of 52% (95% CI, 35%-68%), and an AUCof 0.69; an speech language pathologist's recommendation for nil per os (nothing by mouth) yielded a sensitivity of 50% (95% CI, 27%-73%), a specificity of 94% (95% CI, 79%-98%), and an AUCof 0.72.

conclusionsThe BSE and its components, including the 3-WST, demonstrated variable accuracy for aspiration in survivors of ARF. Investigation to determine the optimal noninvasive test for aspiration in ARF survivors is warranted. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov identifier: NCT02363686, Aspiration in Acute Respiratory Failure Survivors.

Indexed as

Point-of-Care TestingAgedAirway ExtubationCohort StudiesDeglutitionDeglutition DisordersFemaleHumansMaleMiddle AgedRespiratory AspirationRespiratory InsufficiencyROC CurveSensitivity and SpecificitySurvivors

Identifiers

PMID28259057
PMCPMC5481997
OpenAlexW2588670844

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.