Evidence map›Paper›PMID 28258985›Full record

ReviewCurrent opinion in plant biology2017

Gene body DNA methylation in plants.

Adam J Bewick, Robert J Schmitz

Abstract readReview
In one paragraph

Review in Current opinion in plant biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 206 papers.

0numbers the graph read from it
0cells of the map it votes in
206citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

206 citing papers in PubMed.

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  20. Nanorate sequencing reveals theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article

146 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam J BewickDepartment of Genetics, University of Georgia, Athens, GA 30602, USA.
Robert J SchmitzDepartment of Genetics, University of Georgia, Athens, GA 30602, USA. Electronic address: schmitz@uga.edu.

Funding

Identification and Characterization of Population-Wide Epigenetic VariationR00GM100000 · NIGMS · UNIVERSITY OF GEORGIA · PI SCHMITZ, ROBERT J. · 2013 to 2015
$723k
NIGMS NIH HHS R00 GM100000
6 · The paper itself

Abstract

The type, amount, and location of DNA methylation within a gene provides pivotal information on the enzymatic pathway by which it was achieved and its functional consequences. In plants (angiosperms specifically), gene body methylation (gbM) refers to genes with an enrichment of CG DNA methylation within the transcribed regions and depletion at the transcriptional start and termination sites. GbM genes often compose the bulk of methylated genes within angiosperm genomes and are enriched for housekeeping functions. Contrary to the transcriptionally repressive effects of other chromatin modifications within gene bodies, gbM genes are constitutively expressed. GbM has intrigued researchers since its discovery, and much effort has been placed on identifying its functional role. Here, we highlight the recent findings on the evolutionary origin and molecular mechanism of gbM and synthesize studies describing the possible roles for this enigmatic epigenetic phenotype.

Indexed as

DNA MethylationGenes, PlantEvolution, MolecularGene SilencingMagnoliopsida

Identifiers

PMID28258985
PMCPMC5413422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.