Evidence map›Paper›PMID 28258873›Full record

ArticleUltramicroscopy2017

Application of EELS and EFTEM to the life sciences enabled by the contributions of Ondrej Krivanek.

Richard D Leapman

Abstract read
In one paragraph

Article in Ultramicroscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. The 2018 correlative microscopy techniques roadmap.Journal of physics D: Applied physics · 2018
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Richard D LeapmanNational Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda MD 20892, USA. Electronic address: leapmanr@mail.nih.gov.

Funding

Energy-Filtered Electron TomographyZIAEB000037 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI LEAPMAN, RICHARD · 2009 to 2022
$4.2M
Electron microscopy of therapeutic and diagnostic nanoparticlesZIAEB000083 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI LEAPMAN, RICHARD · 2012 to 2019
$1.2M
Intramural NIH HHS ZIA EB000037Intramural NIH HHS ZIA EB000083
6 · The paper itself

Abstract

The pioneering contributions of Ondrej Krivanek to the development of electron energy loss spectrometers, energy filters, and detectors for transmission and scanning transmission electron microscopes have provided researchers with indispensible tools across a wide range of disciplines in the physical sciences, ranging from condensed matter physics, to chemistry, mineralogy, materials science, and nanotechnology. In addition, the same instrumentation has extended its reach into the life sciences, and it is this aspect of Ondrej Krivanek's influential contributions that will be surveyed here, together with some personal recollections. Traditionally, electron microscopy has given a purely morphological view of the biological structures that compose cells and tissues. However, the availability of high-performance electron energy loss spectrometers and energy filters offers complementary information about the elemental and chemical composition at the subcellular scale. Such information has proven to be valuable for applications in cell and structural biology, microbiology, histology, pathology, and more generally in the biomedical sciences.

Indexed as

Biological Science DisciplinesElectronsHumansMicroscopy, Energy-Filtering Transmission ElectronNanotechnologySpectroscopy, Electron Energy-LossCCD camerasDetection limitsDetective quantum efficiencyElectron energy loss spectroscopyEnergy-filtered transmission electron microscopySpectroscopic imagingSTEM-EELS

Identifiers

PMID28258873
PMCPMC5468483

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.