Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2018
Preoperative factors influencing mortality and morbidity in peptic ulcer perforation.
Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Perforated and bleeding peptic ulcer: WSES guidelines.World journal of emergency surgery : WJES · 2020Guideline
- Combined endoscopic and radiologic intervention for management of acute perforated peptic ulcer: a randomized controlled trial.World journal of emergency surgery : WJES · 2022Trial
- Development of a deep-learning model to detect free air on abdominal computed tomography for surgical decision support.International journal of surgery (London, England) · 2026Article
- Evidence-based, cost-effective management of perforated peptic ulcer disease: An algorithm of the Journal of Trauma and Acute Care Surgery Emergency General Surgery Algorithms Working Group.The journal of trauma and acute care surgery · 2026Article
- Predictive Value of the Red Cell Distribution Width-To-Albumin Ratio for Clinical Outcomes in Patients With Peptic Ulcer Perforation.World journal of surgery · 2025Article
- Risk factors and predictive model construction for severe complications following repair of perforated peptic ulcer.Frontiers in surgery · 2025Article
- Article
- Prognostic risk factors in upper gastrointestinal perforation: the role of body composition parameters.Frontiers in nutrition · 2025Article
- Prognostic impact of postoperative management by an intensive care unit intensivist after colonic perforation.Langenbeck's archives of surgery · 2024Article
- Global 30-day morbidity and mortality of surgery for perforated peptic ulcer: GRACE study.Surgical endoscopy · 2024Article
- Laparoscopic Treatment of Perforated Peptic Ulcer: A Propensity Score-Matched Comparison of Interrupted Stitches Repair versus Knotless Barbed Suture.Journal of clinical medicine · 2024Article
- Representation of Women and Women's Health in Australian Medical School Course Outlines, Curriculum Requirements, and Selected Core Clinical Textbooks.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Incidence of Acute Upper Gastrointestinal Bleeding and Related Risk Factors among Elderly Patients Undergoing Surgery for Major Limb Fractures: An Analytical Cohort Study.Healthcare (Basel, Switzerland) · 2023Article
- Immune function, gastrointestinal hormone levels, and their clinical significance in patients with gastric ulcers complicated with depression.World journal of psychiatry · 2023Article
- Incidence of colonoscopy-related perforation and risk factors for poor outcomes: 3-year results from a prospective, multicenter registry (with videos).Surgical endoscopy · 2023Observational
- Perforated peptic ulcer (PPU) treatment: an Italian nationwide propensity score-matched cohort study investigating laparoscopic vs open approach.Surgical endoscopy · 2023Article
- Risk factors for leak after omentopexy for duodenal ulcer perforations.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Editorial: Surgical outcomes in acute care surgery: should we introduce the concept of time-critical condition?Frontiers in surgery · 2023Article
- Early post-operative morbidity and mortality predictors in peptic ulcer perforation.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- A Comparative Study between Peptic Ulcer Perforation Score, Mannheim Peritonitis Index, ASA Score, and Jabalpur Score in Predicting the Mortality in Perforated Peptic Ulcers.Surgery journal (New York, N.Y.) · 2022Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePerforated peptic ulcer is one of the most common surgical emergencies worldwide. With the improvement in medical therapy for peptic ulcers, the number of elective surgical procedures has come down. However, the incidence of perforated peptic ulcer is still increasing and remains as a substantial health problem with significant postoperative morbidity and mortality. This study aimed to find out the association between various preoperative and intraoperative factors with the postoperative mortality and morbidity in patients operated for peptic ulcer perforation.
methodsThis prospective observational study had a time based sample of 101 perforation peritonitis cases admitted to the surgical wards of a tertiary care center from February 2015 to January 2016 who underwent laparotomy, diagnosed to have peptic ulcer perforation and underwent simple closure with an omental patch. Data regarding age, gender, presenting complaints, time elapsed from the onset of symptoms to surgery, physical examination findings, comorbid diseases, laboratory and imaging findings, intraoperative findings, length of hospital stay, postoperative morbidity, and mortality were recorded and analyzed.
resultsFemale gender, older age group, perforation surgery interval more than 36 h, and size of perforation more than 1 cm
conclusionsAn understanding of these factors, identification of patients at risk and early intervention can help in reducing the postoperative morbidity and mortality in peptic ulcer perforation.
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