Evidence map›Paper›PMID 28258153›Full record

ArticleJournal of leukocyte biology2017

Rationalized design of a mucosal vaccine protects against

Mushtaq Ahmed, Hongmei Jiao, Racquel Domingo-Gonzalez, Shibali Das, Kristin L Griffiths, Javier Rangel-Moreno, Uma M Nagarajan, Shabaana A Khader

Abstract read
In one paragraph

Article in Journal of leukocyte biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Infection and immunity · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Synthetic protein conjugate vaccines provide protection againstProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Advancing Adjuvants forFrontiers in immunology · 2021
    Review
  11. Article
  12. 6,6'-Aryl trehalose analogs as potential Mincle ligands.Bioorganic & medicinal chemistry · 2020
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Mushtaq AhmedDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Hongmei JiaoDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Racquel Domingo-GonzalezDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Shibali DasDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Kristin L GriffithsDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA.
Javier Rangel-MorenoDepartment of Medicine, Division of Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, New York, USA; and.
Uma M NagarajanDepartment of Pediatrics and Microbiology/Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Shabaana A KhaderDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA; khader@wustl.edu.
Washington University in St. Louis · USUniversity of North Carolina at Chapel Hill · USUniversity of Rochester Medical Center · USYangzhou University · CN

Funding

ROLE OF IL-17 IN PROTECTIVE VACCINE-INDUCED IMMUNE RESPONSES AGAINST TUBERCULOSISR01HL105427 · NHLBI · WASHINGTON UNIVERSITY · PI KHADER, SHABAANA A. · 2011 to 2025
$5.9M
NHLBI NIH HHS R01 HL105427
6 · The paper itself

Abstract

Pulmonary tuberculosis (TB) caused by

Indexed as

Administration, IntranasalAnimalsBCG VaccineCytokinesDendritic CellsMiceMice, Inbred C57BLMice, KnockoutMucous MembraneMycobacterium tuberculosisTh17 CellsTuberculosis, PulmonaryBCG VaccineCytokinesadjuvantsmucosal immunityTh17/Th1 responsestuberculosis

Identifiers

PMID28258153
PMCPMC5433857
OpenAlexW2593710418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.