Evidence map›Paper›PMID 28258124›Full record

ArticleBMJ (Clinical research ed.)2017

Meta-analytical methods to identify who benefits most from treatments: daft, deluded, or deft approach?

David J Fisher, James R Carpenter, Tim P Morris, Suzanne C Freeman, Jayne F Tierney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ (Clinical research ed.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 56 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 56 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 56 syntheses or guidelines pooled it.

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  8. Interaction of CYP2C19 with the effect of clopidogrel in secondary prevention of major ischemic events: Systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2026
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  18. Exercise-based interventions targeting balance and falls in people with COPD: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
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50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

David J FisherLondon Hub for Trials Methodology Research, MRC Clinical Trials Unit, University College London, London, UK d.fisher@ucl.ac.uk.
James R CarpenterLondon Hub for Trials Methodology Research, MRC Clinical Trials Unit, University College London, London, UK.
Tim P MorrisLondon Hub for Trials Methodology Research, MRC Clinical Trials Unit, University College London, London, UK.
Suzanne C FreemanLondon Hub for Trials Methodology Research, MRC Clinical Trials Unit, University College London, London, UK.
Jayne F TierneyLondon Hub for Trials Methodology Research, MRC Clinical Trials Unit, University College London, London, UK.

Funding

Medical Research Council MC_EX_G0800814Medical Research Council MC_UU_12023/21
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Meta-Analysis as TopicTreatment OutcomeHumansResearch DesignReview Literature as Topic

Identifiers

PMID28258124
PMCPMC5421441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.