Evidence map›Paper›PMID 28258048›Full record

ArticleJMIR research protocols2017

Effectiveness of a 16-Week Multimodal Exercise Program on Individuals With Dementia: Study Protocol for a Multicenter Randomized Controlled Trial.

Sandra Trautwein, Andrea Scharpf, Bettina Barisch-Fritz, Christina Niermann, Alexander Woll

Abstract read
In one paragraph

Article in JMIR research protocols, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Physical activity and the outcome of cognitive trajectory: a machine learning approach.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
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  7. Recommendations for assessing motor performance in individuals with dementia: suggestions of an expert panel - a qualitative approach.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra TrautweinInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID http://orcid.org/0000-0002-1874-0723
Andrea ScharpfInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID http://orcid.org/0000-0003-0901-9288
Bettina Barisch-FritzInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID http://orcid.org/0000-0003-4801-2310
Christina NiermannInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID http://orcid.org/0000-0002-2087-5328
Alexander WollInstitute of Sports and Sports Science, Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID http://orcid.org/0000-0002-5736-2980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing prevalence of dementia in the next decades is accompanied by various societal and economic problems. Previous studies have suggested that physical activity positively affects motor and cognitive skills in individuals with dementia (IWD). However, there is insufficient evidence probably related to several methodological limitations. Moreover, to date adequate physical activity interventions specifically developed for IWD are lacking.

objectiveThis study aims to investigate the effectiveness of a multimodal exercise program (MEP) on motor and cognitive skills in IWD in a high-quality multicenter trial.

methodsA multicenter randomized controlled trial with baseline and postassessments will be performed. It is planned to enroll 405 participants with dementia of mild to moderate stage, aged 65 years and older. The intervention group will participate in a 16-week ritualized MEP especially developed for IWD. The effectiveness of the MEP on the primary outcomes balance, mobility, and gait will be examined using a comprehensive test battery. Secondary outcomes are strength and function of lower limbs, activities of daily living, and cognition (overall cognition, language, processing speed, learning and memory, and visual spatial cognition).

resultsEnrollment for the study started in May 2015. It is planned to complete postassessments by the beginning of 2017. Results are expected to be available in the first half of 2017.

conclusionsThis study will contribute to enhancing evidence for the effects of physical activity on motor and cognitive skills in IWD. Compared to previous studies, this study is characterized by a dementia-specific intervention based on scientific knowledge, a combination of motor and cognitive tasks in the intervention, and high standards regarding methodology. Findings are highly relevant to influence the multiple motor and cognitive impairments of IWD who are often participating in limited physical activity.

trial registrationGerman Clinical Trials Register DRKS00010538; https://drks-neu.uniklinik-freiburg.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00010538 (Archived by WebCite at http://www.webcitation.org/6oVGMbbMD).

Indexed as

activities of daily livingcognitiondementiaexercisegaitphysical activitypostural balance

Identifiers

PMID28258048
PMCPMC5357320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.