Evidence map›Paper›PMID 28257972›Full record

GuidelineThe Journal of allergy and clinical immunology2017

The microbiome in allergic disease: Current understanding and future opportunities-2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology.

Yvonne J Huang, Benjamin J Marsland, Supinda Bunyavanich, Liam O'Mahony, Donald Y M Leung, Antonella Muraro, Thomas A Fleisher

Abstract readGuidelineReview
In one paragraph

Guideline in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed, 5 pooled it
36.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 5 syntheses or guidelines pooled it, 321 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Poor growth in multi-ethnic children with food allergy in Amsterdam.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  20. Article

99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Yvonne J HuangDivision of Pulmonary and Critical Care, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich.
Benjamin J MarslandService de Pneumologie, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Supinda BunyavanichDivision of Allergy and Immunology, Departments of Pediatrics and Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.
Liam O'MahonyMolecular Immunology, Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland.
Donald Y M LeungDivision of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Antonella MuraroFood Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy.
Thomas A FleisherDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Md. Electronic address: tfleishe@mail.nih.gov.
National Institutes of Health Clinical Center · USNational Jewish Health · USPediatrics and Genetics · USUniversity of Lausanne · CHUniversity of Michigan–Ann Arbor · USUniversity of Zurich · CH

Funding

Nasal biomarkers of asthmaR01AI118833 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BUNYAVANICH, SUPINDA · 2015 to 2019
$3.8M
Airway Microbial Community Structure and Function in Chronic AsthmaK23HL105572 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUANG, YVONNE JEAN · 2011 to 2015
$780k
NHLBI NIH HHS K23 HL105572NIAID NIH HHS R01 AI118833
6 · The paper itself

Abstract

PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both.

Indexed as

Allergy and ImmunologyAnimalsHumansHypersensitivityMicrobiotaasthmaatopic dermatitisdysbiosisfood allergyMicrobiomemicrobiotaprebioticprobioticsystems biology

Identifiers

PMID28257972
PMCPMC5899886
OpenAlexW2594112302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.