Evidence map›Paper›PMID 28257708›Full record

ArticleCell stem cell2017

Pericytes or Mesenchymal Stem Cells: Is That the Question?

Elena Cano, Véronique Gebala, Holger Gerhardt

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Signaling Role of Pericytes in Vascular Health and Tissue Homeostasis.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Transcriptional networks controlling stromal cell differentiation.Nature reviews. Molecular cell biology · 2021
    Review
  8. Article
  9. The pericyte: A critical cell in the pathogenesis of CADASIL.Cerebral circulation - cognition and behavior · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Designer Stem Cells: Genome Engineering and the Next Generation of Cell-Based Therapies.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Review
  15. Article
  16. Pericytes in Muscular Dystrophies.Advances in experimental medicine and biology · 2019
    Article
  17. Review
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Elena CanoIntegrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin.
Véronique GebalaIntegrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin.
Holger GerhardtIntegrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin; Berlin Institute of Health (BIH), Kapelle-Ufer 2, 10117 Berlin, Germany; Vascular Patterning Laboratory, Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address: holger.gerhardt@mdc-berlin.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For almost a decade, mesenchymal stem cells (MSCs) were believed to reside as perivascular cells in vivo. In this issue of Cell Stem Cell, Guimarães-Camboa et al. (2017) challenge this idea and use lineage tracing to demonstrate that perivascular cells do not behave as tissue-specific progenitors in various organs, despite showing MSC potential in vitro.

Indexed as

Mesenchymal Stem CellsPericytesCell Differentiation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.