Evidence map›Paper›PMID 28257630›Full record

ArticleInternational journal for equity in health2017

Multifactorial discrimination as a fundamental cause of mental health inequities.

Mariam Khan, Misja Ilcisin, Katherine Saxton

Erratum issuedAbstract read
In one paragraph

Article in International journal for equity in health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Stigma Diminishes the Protective Effect of Social Support on Psychological Distress Among Young Black Men Who Have Sex With Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2018
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  11. Extending Fundamental Cause Theory to Holistic Health.Sociology of health & illness · 2025
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  19. Leaving no one behind: successful ageing at the intersection of ageism and ableism.Philosophy, ethics, and humanities in medicine : PEHM · 2023
    Article
  20. Everyday Discrimination and HIV Testing Among Partnered Latino/x Sexual Minority Men in the United States: A Stratified Analysis by Birth Location.AIDS education and prevention : official publication of the International Society for AIDS Education · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Mariam KhanPublic Health Program, Santa Clara University, 500 El Camino Real, Santa Clara, CA, 95053, USA.
Misja IlcisinPublic Health Program, Santa Clara University, 500 El Camino Real, Santa Clara, CA, 95053, USA.
Katherine SaxtonDepartment of Biology, Santa Clara University, 500 El Camino Real, Santa Clara, CA, 95053, USA. ksaxton@scu.edu.ORCID 0000-0002-6071-2048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe theory of fundamental causes explains why health disparities persist over time, even as risk factors, mechanisms, and diseases change. Using an intersectional framework, we evaluated multifactorial discrimination as a fundamental cause of mental health disparities.

methodsUsing baseline data from the Project STRIDE: Stress, Identity, and Mental Health study, we examined the health effects of discrimination among individuals who self-identified as lesbian, gay, or bisexual. We used logistic and linear regression to assess whether multifactorial discrimination met the four criteria designating a fundamental cause, namely that the cause: 1) influences multiple health outcomes, 2) affects multiple risk factors, 3) involves access to resources that can be leveraged to reduce consequences of disease, and 4) reproduces itself in varied contexts through changing mechanisms.

resultsMultifactorial discrimination predicted high depression scores, psychological well-being, and substance use disorder diagnosis. Discrimination was positively associated with risk factors for high depression scores: chronic strain and total number of stressful life events. Discrimination was associated with significantly lower levels of mastery and self-esteem, protective factors for depressive symptomatology. Even after controlling for risk factors, discrimination remained a significant predictor for high depression scores. Among subjects with low depression scores, multifactorial discrimination also predicted anxiety and aggregate mental health scores.

conclusionsMultifactorial discrimination should be considered a fundamental cause of mental health inequities and may be an important cause of broad health disparities among populations with intersecting social identities.

Indexed as

Mental HealthAdolescentAdultAnxietyAnxiety DisordersDepressionDepressive DisorderFemaleGender IdentityHumansLogistic ModelsMaleMiddle AgedRacial GroupsRisk FactorsSelf ConceptDiscriminationFundamental causesHealth equityIntersectionalityMental Health

Identifiers

PMID28257630
PMCPMC5336641

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.