Evidence map›Paper›PMID 28257554›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2017

Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K

Steven T G Street, Donovan N Chin, Gregory J Hollingworth, Monica Berry, Juan C Morales, M Carmen Galan

Open access · hybridAbstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Naphthalene diimides for G4s.Nature chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Steven T G StreetSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0002-7635-8733
Donovan N ChinNovartis Institutes for Biomedical Research, 250 Massachusetts Ave., Cambridge, Massachusetts, 02139, USA.
Gregory J HollingworthNovartis Institutes for Biomedical Research, Novartis Campus, 4002, Basel, Switzerland.
Monica BerrySchool of Physics, University of Bristol, HH Wills Physics Laboratory, Bristol, BS8 1TL, UK.
Juan C MoralesInstituto de Parasitología y Biomedicina, Avenida del Conocimiento, s/n, 18016, Armilla, Granada, Spain.
M Carmen GalanSchool of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.ORCID http://orcid.org/0000-0001-7307-2871
University of Bristol · GBNovartis (Switzerland) · CHInstituto de Parasitología y Biomedicina "López - Neyra" · ES

Funding

Biotechnology and Biological Sciences Research Council BB/L01386X/1
6 · The paper itself

Abstract

Selective G-quadruplex ligands offer great promise for the development of anti-cancer therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively bind to the hybrid form of the human telomeric G-quadruplex in K

Indexed as

G-QuadruplexesAntineoplastic AgentsBuffersCalorimetryCell Line, TumorCell SurvivalCircular DichroismDrug DesignHeLa CellsHumansImidesLigandsMicroscopy, ConfocalNaphthalenesPotassiumTelomereAntineoplastic AgentsBuffersImidesLigandsnaphthalenediimideNaphthalenesPotassiumantitumour agentscarbohydratesdrug designG-quadruplexesmolecular recognition

Identifiers

PMID28257554
PMCPMC5485019
OpenAlexW2592254449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.