ArticlePloS one2017
Polygalacturonase gene pgxB in Aspergillus niger is a virulence factor in apple fruit.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- FpLaeA Coordinates Fusarium proliferatum Pathogenesis by Orchestrating Mycotoxin Biosynthesis and Host Immune Subversion.Journal of agricultural and food chemistry · 2026Article
- From Hue to Health: Exploring the Therapeutic Potential of Plant-Pigment-Enriched Extracts.Microorganisms · 2025Article
- Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight.BMC genomics · 2025Article
- Revisiting interactions between polygalacturonases and polygalacturonase-inhibiting proteins and their effects on plant health: a review.Frontiers in plant science · 2025Review
- Glycine Enhances Oxidative Stress Tolerance and Biocontrol Efficacy ofFoods (Basel, Switzerland) · 2023Article
- Fungal pectinases: an insight into production, innovations and applications.World journal of microbiology & biotechnology · 2023Review
- Spoilage Monitoring and Early Warning for Apples in Storage Using Gas Sensors and Chemometrics.Foods (Basel, Switzerland) · 2023Article
- Whole Genome Sequencing and Comparative Genomics of Indian Isolates of Wheat Spot Blotch PathogenPathogens (Basel, Switzerland) · 2022Article
- An assessment of the air quality in apple warehouses: new records of Aspergillus europaeus, Aspergillus pulverulentus, Penicillium allii and Penicillium sumatraense as decay agents.Archives of microbiology · 2021Article
- Spray-induced gene silencing for disease control is dependent on the efficiency of pathogen RNA uptake.Plant biotechnology journal · 2021Article
- Role of Exopolygalacturonase-Related Genes in Potato-Pathogens (Basel, Switzerland) · 2021Article
- Proteome-Wide Analysis of Lysine 2-Hydroxyisobutyrylation inFrontiers in microbiology · 2021Article
- A rapid colorimetric LAMP assay for detection of Rhizoctonia solani AG-1 IA causing sheath blight of rice.Scientific reports · 2020Article
- Molecular characterization and race identification of3 Biotech · 2020Article
- Clovamide, a Hydroxycinnamic Acid Amide, Is a Resistance Factor AgainstFrontiers in plant science · 2020Article
- Pectin induced transcriptome of a Rhizoctonia solani strain causing sheath blight disease in rice reveals insights on key genes and RNAi machinery for development of pathogen derived resistance.Plant molecular biology · 2019Article
- The Multifaceted Role of Pectin Methylesterase Inhibitors (PMEIs).International journal of molecular sciences · 2018Review
- Correction: Polygalacturonase gene pgxB in Aspergillus niger is a virulence factor in apple fruit.PloS one · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus niger, a saprophytic fungus, is widely distributed in soil, air and cereals, and can cause postharvest diseases in fruit. Polygalacturonase (PG) is one of the main enzymes in fungal pathogens to degrade plant cell wall. To evaluate whether the deletion of an exo-polygalacturonase gene pgxB would influence fungal pathogenicity to fruit, pgxB gene was deleted in Aspergillus niger MA 70.15 (wild type) via homologous recombination. The ΔpgxB mutant showed similar growth behavior compared with the wild type. Pectin medium induced significant higher expression of all pectinase genes in both wild type and ΔpgxB in comparison to potato dextrose agar medium. However, the ΔpgxB mutant was less virulent on apple fruits as the necrosis diameter caused by ΔpgxB mutant was significantly smaller than that of wild type. Results of quantitive-PCR showed that, in the process of infection in apple fruit, gene expressions of polygalacturonase genes pgaI, pgaII, pgaA, pgaC, pgaD and pgaE were enhanced in ΔpgxB mutant in comparison to wild type. These results prove that, despite the increased gene expression of other polygalacturonase genes in ΔpgxB mutant, the lack of pgxB gene significantly reduced the virulence of A. niger on apple fruit, suggesting that pgxB plays an important role in the infection process on the apple fruit.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.