Evidence map›Paper›PMID 28257169›Full record

Trial reportAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2017

Filtration Markers, Cardiovascular Disease, Mortality, and Kidney Outcomes in Stable Kidney Transplant Recipients: The FAVORIT Trial.

M C Foster, D E Weiner, A G Bostom, M A Carpenter, L A Inker, P Jarolim, A A Joseph, J W Kusek, T Pesavento, M A Pfeffer and 3 more

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Combined Creatinine and Cystatin C Equations Improve Estimation of Glomerular Filtration Rate in Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  3. Article
  4. Article
  5. GFR estimated with creatinine rather than cystatin C is more reflective of the true risk of adverse outcomes with low GFR in kidney transplant recipients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  6. Review
  7. Review
  8. Role of novel biomarkers in kidney transplantation.World journal of transplantation · 2020
    Review
  9. Observational
  10. Observational
  11. Article
  12. Article
  13. The prognostic values of beta-2 microglobulin for risks of cardiovascular events and mortality in the elderly patients with isolated systolic hypertension.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

M C FosterDivision of Nephrology, Tufts Medical Center, Boston, MA.
D E WeinerDivision of Nephrology, Tufts Medical Center, Boston, MA.
A G BostomRhode Island Hospital, Providence, RI.
M A CarpenterDepartment of Biostatistics, University of North Carolina, Chapel Hill, NC.
L A InkerDivision of Nephrology, Tufts Medical Center, Boston, MA.
P JarolimDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
A A JosephDivision of Nephrology, Tufts Medical Center, Boston, MA.
J W KusekNational Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
T PesaventoThe Ohio State University Medical Center, Columbus, OH.
M A PfefferDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
M RaoDivision of Nephrology, Tufts Medical Center, Boston, MA.
S D SolomonDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
A S LeveyDivision of Nephrology, Tufts Medical Center, Boston, MA.
Tufts Medical Center · USBrigham and Women's Hospital · USHarvard University · USNational Institute of Diabetes and Digestive and Kidney Diseases · USRhode Island Hospital · USThe Ohio State University · USUniversity of North Carolina at Chapel Hill · US

Funding

Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) TrialU01DK061700 · NIDDK · TUFTS MEDICAL CENTER · PI BOSTOM, ANDREW G. · 2001 to 2011
$29.0M
NIDDK NIH HHS U01 DK061700
6 · The paper itself

Abstract

Cystatin C and beta-2-microglobulin (B2M) are filtration markers associated with adverse outcomes in nontransplant populations, sometimes with stronger associations than for creatinine. We evaluated associations of estimated glomerular filtration rate from cystatin C (eGFR

Indexed as

AdultAgedbeta 2-MicroglobulinBiomarkersCardiovascular DiseasesCreatinineCystatin CDouble-Blind MethodFemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionGraft SurvivalHumansImmunosuppressive AgentsKidney Failure, Chronicbeta 2-MicroglobulinBiomarkersCreatinineCystatin CImmunosuppressive Agentsbiomarkerclinical research/practiceglomerular filtration rate (GFR)kidney (native) function/dysfunctionkidney transplantation/nephrology

Identifiers

PMID28257169
PMCPMC5573607
OpenAlexW2594194894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.