Evidence map›Paper›PMID 28257063›Full record

ArticleFoods (Basel, Switzerland)2017

Red Yeast Rice.

Thu Nguyen, Mitchell Karl, Antonello Santini

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Two-Step Engineering of Food-GradeJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Clinical pharmacology : advances and applications · 2025
    Review
  8. Article
  9. Article
  10. Inclisiran-A Revolutionary Addition to a Cholesterol-Lowering Therapy.International journal of molecular sciences · 2023
    Review
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Assimilation of Cholesterol byJournal of fungi (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Thu NguyenBoca Raton Hospital Campus, Internal Medicine Residency Program, FAU/ Schmidt School of Medicine, Boca Raton, FL 33486, USA. nguyent@health.fau.edu.
Mitchell KarlBoca Raton Hospital Campus, Internal Medicine Residency Program, FAU/ Schmidt School of Medicine, Boca Raton, FL 33486, USA. karlm@health.fau.edu.
Antonello SantiniDepartment of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, Napoli 80131, Italy. asantini@unina.it.
Boca Raton Regional Hospital · USUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for a long time in Asian cuisine and traditional medicine. It consists of multiple bioactive substances, including monacolins, which potentially can be used as a nutraceutical. Monacolin K, which is chemically identical to lovastatin, has been recognized as responsible for the cholesterolreducing effect of this compound. While the European Food Safety Authority maintains that the use of monacolin K from RYR preparations of at least 10 mg can produce a normal blood cholesterol level, the United States Food and Drug Administration considers monacolin K, due to its similarity with lovastatin, an unapproved drug, and therefore marketing of products that label the monacolin content is prohibited. This mini-review summarizes the benefit of RYR in hyperlipidemia, maintains RYR use as a food, and addresses the importance of regulation regarding RYR and the need for clinical data and clear label information for consumers with reference to a toxin-free, nonaugmented, standardized amount of monacolins.

Indexed as

healthlovastatinnutraceuticalred yeast ricesafety

Identifiers

PMID28257063
PMCPMC5368538
OpenAlexW2593271859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.