Evidence map›Paper›PMID 28257035›Full record

ArticleInternational journal of molecular sciences2017

RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells.

Shubham Dayal, Jun Zhou, Praveen Manivannan, Mohammad Adnan Siddiqui, Omaima Farid Ahmad, Matthew Clark, Sahezeel Awadia, Rafael Garcia-Mata, Lirim Shemshedini, Krishnamurthy Malathi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Uridine as a hub in cancer metabolism and RNA biology.Experimental & molecular medicine · 2025
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  10. LncRNAEpigenomics · 2020
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shubham DayalDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Shubham.Dayal@rockets.utoledo.edu.
Jun ZhouDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Jun.zhou@rockets.utoledo.edu.
Praveen ManivannanDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Praveen.Manivannan@rockets.utoledo.edu.
Mohammad Adnan SiddiquiDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Mohammad.Siddiqui@rockets.utoledo.edu.
Omaima Farid AhmadDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Omaima.Ahmad@rockets.utoledo.edu.
Matthew ClarkDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. clark.matt11@gmail.com.
Sahezeel AwadiaDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Sahezeel.Awadia@rockets.utoledo.edu.
Rafael Garcia-MataDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Rafael.GarciaMata@utoledo.edu.
Lirim ShemshediniDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Lirim.Shemshedini@utoledo.edu.
Krishnamurthy MalathiDepartment of Biological Sciences, 2801 W. Bancroft St., University of Toledo, Toledo, OH 43606, USA. Malathi.Krishnamurthy@utoledo.edu.
University of Toledo · US

Funding

Novel role of RNA signaling in cross-talk between autophagy and apoptosisR15AI119980 · NIAID · UNIVERSITY OF TOLEDO · PI KRISHNAMURTHY, MALATHI · 2016 to 2016
$443k
Role of small RNAs in innate immunity and inflammationR15AI089518 · NIAID · UNIVERSITY OF TOLEDO · PI KRISHNAMURTHY, MALATHI · 2010 to 2010
$430k
Regulation of Invadopodia Formation by RhoG Specific GEFs and GAPsR15CA199101 · NCI · UNIVERSITY OF TOLEDO · PI GARCIA-MATA, RAFAEL · 2016 to 2016
$409k
RhoG Signaling in InvadopodiaR21CA194776 · NCI · UNIVERSITY OF TOLEDO · PI GARCIA-MATA, RAFAEL · 2016 to 2017
$331k
NCI NIH HHS R15 CA199101NCI NIH HHS R21 CA194776NIAID NIH HHS R15 AI089518NIAID NIH HHS R15 AI119980
6 · The paper itself

Abstract

The interferon antiviral pathways and prostate cancer genetics converge on a regulated endoribonuclease, RNase L. Positional cloning and linkage studies mapped Hereditary Prostate Cancer 1 (

Indexed as

Signal TransductionCell AdhesionCell Line, TumorCell MovementEndoribonucleasesEnzyme ActivationHumansMaleMatrix MetalloproteinasesMutationProstatic NeoplasmsProtein BindingProtein StabilityReceptors, Androgen2-5A-dependent ribonucleaseEndoribonucleasesMatrix MetalloproteinasesReceptors, Androgenandrogen receptorfilamin Aprostate cancerRNase L

Identifiers

PMID28257035
PMCPMC5372545
OpenAlexW2593696494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.