Evidence map›Paper›PMID 28256626›Full record

ArticleScientific reports2017

Treatment of steroid-induced osteonecrosis of the femoral head using porous Se@SiO

Guoying Deng, Kerun Niu, Feng Zhou, Buxiao Li, Yingjie Kang, Xijian Liu, Junqing Hu, Bo Li, Qiugen Wang, Chengqing Yi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Porous Se@SiOTranslational andrology and urology · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Porous Se@SiOInternational journal of nanomedicine · 2019
    Article
  18. Se@SiORSC advances · 2018
    Article
  19. Porous Se@SiOInternational journal of nanomedicine · 2018
    Article
  20. Porous Se@SiOInternational journal of nanomedicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Guoying DengTrauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 Xin Songjiang Road, Shanghai 201620, P.R. China.
Kerun NiuDepartment of Orthopedics, Shanghai Bone Tumor Institute, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, P.R. China.
Feng ZhouDepartment of Orthopedics, Shanghai Bone Tumor Institute, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, P.R. China.
Buxiao LiTrauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 Xin Songjiang Road, Shanghai 201620, P.R. China.
Yingjie KangDepartment of Radiology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine. No. 528, Zhangheng Road, Shanghai 201203, P.R. China.
Xijian LiuCollege of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai, 201620, P.R. China.
Junqing HuState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, P.R. China.
Bo LiState Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, No. 1295 Dingxi Road, Shanghai 200050, People's Republic of China.
Qiugen WangTrauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 Xin Songjiang Road, Shanghai 201620, P.R. China.
Chengqing YiDepartment of Orthopedics, Shanghai Bone Tumor Institute, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, P.R. China.
Qian WangTrauma Center, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 650 Xin Songjiang Road, Shanghai 201620, P.R. China.
Donghua University · CNShanghai First People's Hospital · CNChinese Academy of Sciences · CNShanghai Jiao Tong University · CNShanghai Medical College of Fudan University · CNShanghai University of Engineering Science · CNShuguang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reducing oxidative stress (ROS) have been demonstrated effective for steroid-induced osteonecrosis of the femoral head (steroid-induced ONFH). Selenium (Se) plays an important role in suppressing oxidative stress and has huge potential in ONFH treatments. However the Se has a narrow margin between beneficial and toxic effects which make it hard for therapy use in vivo. In order to make the deficiency up, a control release of Se (Se@SiO

Indexed as

AnimalsAntioxidantsFemurNanocompositesOsteonecrosisRats, Sprague-DawleyReactive Oxygen SpeciesSeleniumSilicon DioxideSteroidsTreatment OutcomeAntioxidantsReactive Oxygen SpeciesSeleniumSilicon DioxideSteroids

Identifiers

PMID28256626
PMCPMC5335566
OpenAlexW2594017336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.