Evidence map›Paper›PMID 28256607›Full record

ArticleScientific reports2017

The Rotavirus NSP4 Viroporin Domain is a Calcium-conducting Ion Channel.

Thieng Pham, Jacob L Perry, Timothy L Dosey, Anne H Delcour, Joseph M Hyser

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Frontiers in microbiology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Host IPmBio · 2024
    Article
  19. Intercellular Transport of Viral Proteins.Results and problems in cell differentiation · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thieng PhamDepartment of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Jacob L PerryAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Timothy L DoseyVerna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX, USA.
Anne H DelcourDepartment of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Joseph M HyserAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USUniversity of Houston · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag · 2001 to 2026
$28.3M
HOUSTON AREA MOLECULAR BIOPHYSICS TRAINING PROGRAMT32GM008280 · NIGMS · RICE UNIVERSITY · PI WENSEL, THEODORE G · 1988 to 2023
$8.0M
Enteric Virus Calcium Channel InhibitorsK01DK093657 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI HYSER, JOSEPH M. · 2012 to 2016
$639k
NIAID NIH HHS P30 AI027767NIDDK NIH HHS K01 DK093657NIDDK NIH HHS P30 DK056338NIGMS NIH HHS T32 GM008280
6 · The paper itself

Abstract

Viroporins are small virus-encoded ion channel proteins. Most viroporins are monovalent selective cation channels, with few showing the ability to conduct divalent cations, like calcium (Ca

Indexed as

Amino Acid SequenceBariumCalciumCalcium ChannelsCholesterolEscherichia coliGene ExpressionGlycoproteinsIon TransportMembrane PotentialsMutationPatch-Clamp TechniquesPeptidesPhosphatidylcholinesProteolipidsRecombinant Proteins1,2-diphytanoylphosphatidylcholineasolectinBariumCalciumCalcium ChannelsCholesterolGlycoproteinsNS28 protein, rotavirusPeptidesPhosphatidylcholinesProteolipidsproteoliposomesRecombinant ProteinsToxins, BiologicalUnilamellar LiposomesViral Nonstructural Proteins

Identifiers

PMID28256607
PMCPMC5335360
OpenAlexW2594230304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.