Evidence map›Paper›PMID 28256593›Full record

ArticleScientific reports2017

TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury.

Jeffrey D Pressly, Taketsugu Hama, Shannon O' Brien, Kevin R Regner, Frank Park

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. TRIM21 inhibition alleviates acute kidney injury by promoting INTS3-associated DNA damage repair.Apoptosis : an international journal on programmed cell death · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Role of TRIP13 in human cancer development.Molecular biology reports · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Insights into a Crucial Role of TRIP13 in Human Cancer.Computational and structural biotechnology journal · 2019
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeffrey D PresslyThe University of Tennessee Health Science Center, College of Pharmacy, Department of Pharmaceutical Sciences, Memphis, TN, USA.
Taketsugu HamaThe University of Tennessee Health Science Center, College of Pharmacy, Department of Pharmaceutical Sciences, Memphis, TN, USA.
Shannon O' BrienThe University of Tennessee Health Science Center, College of Pharmacy, Department of Pharmaceutical Sciences, Memphis, TN, USA.
Kevin R RegnerMedical College of Wisconsin, Department of Medicine, Division of Nephrology, Milwaukee, WI, USA.
Frank ParkThe University of Tennessee Health Science Center, College of Pharmacy, Department of Pharmaceutical Sciences, Memphis, TN, USA.
University of Tennessee Health Science Center · USMedical College of Wisconsin · US

Funding

AGS3 in Ischemic Renal InjuryR01DK090123 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI PARK, FRANK, REGNER, KEVIN R. · 2011 to 2015
$1.5M
NIDDK NIH HHS R01 DK090123
6 · The paper itself

Abstract

Damage to renal tubular epithelial cells by genetic, environmental, or biological insults can initiate complex signaling mechanisms that promote kidney repair and functional recovery. In this study, we demonstrated that thyroid receptor interacting protein 13 (TRIP13) is a critical modulator of tubular epithelial cell repair following ischemia-reperfusion injury (IRI), a common type of renal stressor. In Trip13

Indexed as

ApoptosisAcute Kidney InjuryAnimalsATPases Associated with Diverse Cellular ActivitiesCell Cycle ProteinsDNA-Binding ProteinsEpithelial CellsMiceProtein BindingReperfusion InjuryTranscription FactorsTumor Suppressor Protein p53ATPases Associated with Diverse Cellular ActivitiesCell Cycle ProteinsDNA-Binding ProteinsTranscription FactorsTrip13 protein, mouseTrp53 protein, mouseTtc5 protein, mouseTumor Suppressor Protein p53

Identifiers

PMID28256593
PMCPMC5335694
OpenAlexW2593705105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.