ArticleScientific reports2017
Production of the medaka derived from vitrified whole testes by germ cell transplantation.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 77 citations in OpenAlex.
- Germ cell manipulation in farmed fishes.The Journal of reproduction and development · 2026Review
- Inhibiting invasive fish reproduction via germ cell xenotransplantation and hybrid lethality.Scientific reports · 2025Article
- Production of all-male non-transgenic zebrafish by conditional primordial germ cell ablation.Fish physiology and biochemistry · 2023Article
- Enhancement of zebrafish sperm production via a large body-sized surrogate with germ cell transplantation.Communications biology · 2023Article
- Allogeneic testes transplanted into partially castrated adult medaka (Oryzias latipes) can produce donor-derived offspring by natural mating over a prolonged period.Zoological letters · 2022Article
- Spermatogonia From Cryopreserved Testes of Critically Endangered Chinese Sturgeon Efficiently Colonized and Preferentially Proliferated in the Recipient Gonads of Yangtze Sturgeon.Marine biotechnology (New York, N.Y.) · 2022Article
- Advantages, Factors, Obstacles, Potential Solutions, and Recent Advances of Fish Germ Cell Transplantation for Aquaculture-A Practical Review.Animals : an open access journal from MDPI · 2022Review
- Models and Molecular Markers of Spermatogonial Stem Cells in Vertebrates: To Find Models in Nonmammals.Stem cells international · 2022Review
- Effects of Hydrostatic Pressure Treatment of Newly Fertilized Eggs on the Ploidy Level and Karyotype of PikeperchLife (Basel, Switzerland) · 2021Article
- Cryopreservation of Germ Cells of Banana Shrimp (Fenneropenaeus merguiensis) and Black Tiger Shrimp (Penaeus monodon).Marine biotechnology (New York, N.Y.) · 2021Article
- Successful Spermatogonial Stem Cells Transplantation within Pleuronectiformes: First Breakthrough at inter-family Level in Marine Fish.International journal of biological sciences · 2021Article
- Cryopreservation of testicular tissue from Murray River Rainbowfish, Melanotaenia fluviatilis.Scientific reports · 2020Article
- Enhanced Enrichment of Medaka Ovarian Germline Stem Cells by a Combination of Density Gradient Centrifugation and Differential Plating.Biomolecules · 2020Article
- Production of Chinese rosy bitterling offspring derived from frozen and vitrified whole testis by spermatogonial transplantation.Fish physiology and biochemistry · 2020Article
- Preservation of zebrafish genetic resources through testis cryopreservation and spermatogonia transplantation.Scientific reports · 2019Article
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- Generation of all-male-like sterile zebrafish by eliminating primordial germ cells at early development.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The medaka (Oryzias latipes) is a teleost model distinguished from other model organisms by the presence of inbred strains, wild stocks, and related species. Cryopreservation guarantees preservation of these unique biological resources. However, because of their large size, cryopreservation techniques for their eggs and embryos have not been established. In the present study, we established a methodology to produce functional gametes from cryopreserved testicular cells (TCs). Whole testes taken from medaka were cryopreserved by vitrification. After thawing, the cells dissociated from cryopreserved testicular tissues were intraperitoneally transplanted into sterile triploid hatchlings. Some cells, presumably spermatogonial stem cells, migrated into the genital ridges of recipients and resulted in the production of eggs or sperm, based on sex of the recipient. Mating of recipients resulted in successful production of cryopreserved TC-derived offspring. We successfully produced individuals from the Kaga inbred line, an endangered wild population in Tokyo, and a sub-fertile mutant (wnt4b
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