Evidence map›Paper›PMID 28256382›Full record

ReviewPresse medicale (Paris, France : 1983)2017

Agents of change: The role of healthcare workers in the prevention of nosocomial and occupational tuberculosis.

Ruvandhi R Nathavitharana, Patricia Bond, Angela Dramowski, Koot Kotze, Philip Lederer, Ingrid Oxley, Jurgens A Peters, Chanel Rossouw, Helene-Mari van der Westhuizen, Bart Willems and 6 more

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Presse medicale (Paris, France : 1983), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Occupational Risk of AirborneInternational journal of environmental research and public health · 2021
    Article
  14. Review
  15. Review
  16. Tuberculous appendicitis: A review of reported cases over the past 10 years.Journal of clinical tuberculosis and other mycobacterial diseases · 2021
    Review
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 5 countries.

Ruvandhi R NathavitharanaTB Proof, Cape Town, South Africa; Beth Israel Deaconess Medical Center, Division of Infectious Diseases, Boston, MA 02215, USA. Electronic address: rnathavi@bidmc.harvard.edu.
Patricia BondTB Proof, Cape Town, South Africa.
Angela DramowskiTB Proof, Cape Town, South Africa; Paediatric Infectious Diseases, Stellenbosch University, Department of Paediatrics and Child Health, Cape Town, South Africa.
Koot KotzeTB Proof, Cape Town, South Africa; East London Hospital Complex, East London, South Africa.
Philip LedererTB Proof, Cape Town, South Africa; Massachusetts General Hospital, Division of Infectious Diseases, , Boston, MA 02215, USA.
Ingrid OxleyNelson Mandela Metropolitan University, Dietetics Division, , Port Elizabeth, South Africa.
Jurgens A PetersTB Proof, Cape Town, South Africa; London School of Hygiene and Tropical Medicine, Faculty of Infectious and Tropical Diseases, Clinical Research Department, London, UK.
Chanel RossouwTB Proof, Cape Town, South Africa.
Helene-Mari van der WesthuizenTB Proof, Cape Town, South Africa; East London Hospital Complex, East London, South Africa.
Bart WillemsTB Proof, Cape Town, South Africa; Stellenbosch University, Division of Community Health, Faculty of Medicine and Health Sciences, , Cape Town, South Africa.
Tiong Xun TingTB Proof, Cape Town, South Africa; Clinical Research Center, Sarawak General Hospital, Kuching, Sarawak, Malaysia.
Arne von DelftTB Proof, Cape Town, South Africa; School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, 7925 Observatory, South Africa.
Dalene von DelftTB Proof, Cape Town, South Africa.
Raquel DuarteInstitute of Public Health, Porto University, EpiUnit, Portugal; Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia, Portugal.
Edward NardellBrigham and Women's Hospital, Division of Global Health and Social Medicine, 02115 Boston, MA, USA.
Alimuddin ZumlaTB Proof, Cape Town, South Africa; University College London, and NIHR Biomedical Research Centre, University College London Hospital, Division of Infection and Immunity, London, UK.
Frere Hospital · ZAWestern Cape Department of Health · ZABeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMassachusetts General Hospital · USNelson Mandela University · ZASarawak General Hospital · MYUCL Biomedical Research Centre · GBUniversidade do Porto · PTUniversity of Cape Town · ZAUniversity of London · GB

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Innovative Interdisciplinary Approaches to Sustainable Airborne Infection ControlD43TW009379 · FIC · BRIGHAM AND WOMEN'S HOSPITAL · PI NARDELL, EDWARD A. · 2012 to 2016
$1.9M
FIC NIH HHS D43 TW009379NIAID NIH HHS P30 AI060354NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

Healthcare workers (HCWs) play a central role in global tuberculosis (TB) elimination efforts but their contributions are undermined by occupational TB. HCWs have higher rates of latent and active TB than the general population due to persistent occupational TB exposure, particularly in settings where there is a high prevalence of undiagnosed TB in healthcare facilities and TB infection control (TB-IC) programmes are absent or poorly implemented. Occupational health programmes in high TB burden settings are often weak or non-existent and thus data that record the extent of the increased risk of occupational TB globally are scarce. HCWs represent a limited resource in high TB burden settings and occupational TB can lead to workforce attrition. Stigma plays a role in delayed diagnosis, poor treatment outcomes and impaired well-being in HCWs who develop TB. Ensuring the prioritization and implementation of TB-IC interventions and occupational health programmes, which include robust monitoring and evaluation, is critical to reduce nosocomial TB transmission to patients and HCWs. The provision of preventive therapy for HCWs with latent TB infection (LTBI) can also prevent progression to active TB. Unlike other patient groups, HCWs are in a unique position to serve as agents of change to raise awareness, advocate for necessary resource allocation and implement TB-IC interventions, with appropriate support from dedicated TB-IC officers at the facility and national TB programme level. Students and community health workers (CHWs) must be engaged and involved in these efforts. Nosocomial TB transmission is an urgent public health problem and adopting rights-based approaches can be helpful. However, these efforts cannot succeed without increased political will, supportive legal frameworks and financial investments to support HCWs in efforts to decrease TB transmission.

Indexed as

Consumer AdvocacyHealth PersonnelCross InfectionFemaleHuman RightsHumansInfection ControlInfectious Disease Transmission, Patient-to-ProfessionalInfectious Disease Transmission, Professional-to-PatientLaboratory PersonnelLatent TuberculosisMaleOccupational DiseasesOccupational ExposureOccupational Health ServicesReturn to Work

Identifiers

PMID28256382
PMCPMC5930005
OpenAlexW2594050498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.