Evidence map›Paper›PMID 28256343›Full record

ArticleUltrasound in medicine & biology2017

Evaluation of Coronary Artery Disease Using Myocardial Elastography with Diverging Wave Imaging: Validation against Myocardial Perfusion Imaging and Coronary Angiography.

Julien Grondin, Marc Waase, Alok Gambhir, Ethan Bunting, Vincent Sayseng, Elisa E Konofagou

Abstract readValidation Study
In one paragraph

Article in Ultrasound in medicine & biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Optimization of Transmit Parameters in Cardiac Strain Imaging With Full and Partial Aperture Coherent Compounding.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Julien GrondinDepartment of Biomedical Engineering, Columbia University, New York, New York, USA.
Marc WaaseDepartment of Medicine, Columbia University, New York, New York, USA.
Alok GambhirDepartment of Medicine, Columbia University, New York, New York, USA.
Ethan BuntingDepartment of Biomedical Engineering, Columbia University, New York, New York, USA.
Vincent SaysengDepartment of Biomedical Engineering, Columbia University, New York, New York, USA.
Elisa E KonofagouDepartment of Biomedical Engineering, Columbia University, New York, New York, USA; Department of Radiology, Columbia University, New York, New York, USA. Electronic address: Ek2191@columbia.edu.
Columbia University · US

Funding

EARLY DETECTION AND MAPPING OF ISCHEMIA USING MYOCARDIAL ELASTOGRAPHYR01EB006042 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI KONOFAGOU, ELISA E. · 2006 to 2018
$4.3M
NIBIB NIH HHS R01 EB006042
6 · The paper itself

Abstract

Myocardial elastography (ME) is an ultrasound-based technique that can image 2-D myocardial strains. The objectives of this study were to illustrate that 2-D myocardial strains can be imaged with diverging wave imaging and differ, on average, between normal and coronary artery disease (CAD) patients. In this study, 66 patients with symptoms of CAD were imaged with myocardial elastography before a nuclear stress test or an invasive coronary angiography. Radial cumulative strains were estimated in all patients. The end-systolic radial strain in the total cross section of the myocardium was significantly higher in normal patients (17.9 ± 8.7%) than in patients with reversible perfusion defect (6.2 ± 9.3%, p < 0.001) and patients with significant (-0.9 ± 7.4%, p < 0.001) and non-significant (3.7 ± 5.7%, p < 0.01) lesions. End-systolic radial strain in the left anterior descending, left circumflex and right coronary artery territory was found to be significantly higher in normal patients than in CAD patients. These preliminary findings indicate that end-systolic radial strain measured with ME is higher on average in healthy persons than in CAD patients and that ME has the potential to be used for non-invasive, radiation-free early detection of CAD.

Indexed as

AgedCoronary AngiographyCoronary Artery DiseaseCoronary VesselsElasticity Imaging TechniquesFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedMyocardial Perfusion ImagingReproducibility of ResultsSensitivity and SpecificityCardiac strain imagingCoronary angiographyCoronary artery diseaseDiverging wave imagingMyocardial perfusion imaging

Identifiers

PMID28256343
PMCPMC5385294
OpenAlexW2594084253

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.