Evidence map›Paper›PMID 28256151›Full record

ReviewThe British journal of radiology2017

The emerging potential of magnetic resonance imaging in personalizing radiotherapy for head and neck cancer: an oncologist's perspective.

Kee H Wong, Rafal Panek, Shreerang A Bhide, Christopher M Nutting, Kevin J Harrington, Katie L Newbold

Abstract readReview
In one paragraph

Review in The British journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Transoral robotic surgery in Ireland: the beginning.Irish journal of medical science · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. The rationale for MR-only treatment planning for external radiotherapy.Clinical and translational radiation oncology · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kee H Wong1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Rafal Panek1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Shreerang A Bhide1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Christopher M Nutting1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Kevin J Harrington1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Katie L Newbold1 Head and neck unit, The Royal Marsden Hospital, London, UK.
Institute of Cancer Research · GBRoyal Marsden Hospital · GB

Funding

Cancer Research UK 13407Medical Research Council MC_EX_MR/M009068/1Medical Research Council MR/M009068/1
6 · The paper itself

Abstract

Head and neck cancer (HNC) is a challenging tumour site for radiotherapy delivery owing to its complex anatomy and proximity to organs at risk (OARs) such as the spinal cord and optic apparatus. Despite significant advances in radiotherapy planning techniques, radiation-induced morbidities remain substantial. Further improvement would require high-quality imaging and tailored radiotherapy based on intratreatment response. For these reasons, the use of MRI in radiotherapy planning for HNC is rapidly gaining popularity. MRI provides superior soft-tissue contrast in comparison with CT, allowing better definition of the tumour and OARs. The lack of additional radiation exposure is another attractive feature for intratreatment monitoring. In addition, advanced MRI techniques such as diffusion-weighted, dynamic contrast-enhanced and intrinsic susceptibility-weighted MRI techniques are capable of characterizing tumour biology further by providing quantitative functional parameters such as tissue cellularity, vascular permeability/perfusion and hypoxia. These functional parameters are known to have radiobiological relevance, which potentially could guide treatment adaptation based on their changes prior to or during radiotherapy. In this article, we first present an overview of the applications of anatomical MRI sequences in head and neck radiotherapy, followed by the potentials and limitations of functional MRI sequences in personalizing therapy.

Indexed as

HeadHead and Neck NeoplasmsHumansMagnetic Resonance ImagingNeckOncologistsPrecision MedicineRadiotherapy Planning, Computer-Assisted

Identifiers

PMID28256151
PMCPMC5601510
OpenAlexW2593857976

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.