Evidence map›Paper›PMID 28255801›Full record

ArticleHeart and vessels2017

Factors and values at admission that predict a fulminant course of acute myocarditis: data from Tokyo CCU network database.

Osamu Inaba, Yasuhiro Satoh, Mitsuaki Isobe, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Osamu InabaTokyo CCU Network Scientific Committee, Tokyo, Japan. oinbcvm@tmd.ac.jp.
Yasuhiro SatohTokyo CCU Network Scientific Committee, Tokyo, Japan.
Mitsuaki IsobeTokyo CCU Network Scientific Committee, Tokyo, Japan.
Takeshi YamamotoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Ken NagaoTokyo CCU Network Scientific Committee, Tokyo, Japan.
Morimasa TakayamaTokyo CCU Network Scientific Committee, Tokyo, Japan.
Shibuya University Network · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prognosis of acute myocarditis is generally benign, but fulminant cases exist which require advanced life support devices, such as percutaneous cardio-pulmonary support (PCPS) and ventricular assist devices (VAD), and lead to fatal outcomes. The purpose of this study was to identify predictors and their values at admission which might foreshadow a fulminant course of myocarditis. Data from 138 patients (mean age 42.0 years, 79 males) with a diagnosis of acute myocarditis in the Tokyo CCU Network database from 2007 to 2009 were analyzed retrospectively. Patients were divided into fulminant (in-hospital death, or PCPS or VAD requirement, N = 42) and non-fulminant groups (N = 96). Clinical data at admission were compared between them. Overall in-hospital mortality was 14.5%. On multivariate analysis, low systolic blood pressure (BPsys, odds ratio (OR)/mmHg 0.97; 95% confidence interval (CI) 0.93-1.00, p = 0.032) and electrocardiographic QRS complex prolongation (OR/10 ms 1.28; 95% CI 1.10-1.59, p = 0.0034) at admission were independent factors associated with a fulminant course. By receiver operator characteristic curve analysis, the area under the curve predicting a fulminant course was 0.769 for low BPsys and 0.821 for prolongation of QRS duration. The optimal cut-off value was 101 mmHg for BPsys (sensitivity 79.5%, specificity 68.0%), and 120 ms for QRS duration (sensitivity 72.2%, specificity 88.0%). Systolic hypotension and prolonged QRS on admission are predictors of a fulminant course of myocarditis.

Indexed as

Disease ManagementHeart-Assist DevicesRegistriesAcute DiseaseAdolescentAdultDisease ProgressionElectrocardiographyFemaleFollow-Up StudiesHumansIncidenceJapanMaleMiddle AgedMyocarditisAcute myocarditisFulminant myocarditisPercutaneous cardio-pulmonary supportPredictors

Identifiers

PMID28255801
OpenAlexW2593675116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.