ArticleEuropean journal of nutrition2018
Season, dietary factors, and physical activity modify 25-hydroxyvitamin D concentration during pregnancy.
Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01723852 (Vitamin D Intervention in Infants), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vitamin D Intervention in Infants
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Vitamin D levels and its influencing factors in children and adolescents in mainland China: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Vitamin D supplementation in the first 2 years and autism spectrum traits at 6-8 years - a randomized clinical trial.Journal of child psychology and psychiatry, and allied disciplines · 2026Trial
- Low-grade inflammation from prenatal period to age 6-8 years in a Vitamin D trial.Pediatric research · 2024Trial
- Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and Infection in Healthy Infants: A Randomized Clinical Trial.JAMA pediatrics · 2018Trial
- Vitamin D status among pregnant women of North Macedonia: Assessing deficiency rates and associated risks factors.Journal of medical biochemistry · 2025Article
- The potential impact of the extended vitamin D fortification policy during pregnancy varies by continent of origin - a population-representative Swedish cohort.European journal of nutrition · 2025Article
- Maternal vitamin D levels during pregnancy and offspring schizophrenia.Schizophrenia research · 2024Article
- Vitamin D levels of pregnant immigrant women and developmental disorders of language, learning and coordination in offspring.PloS one · 2024Article
- Influence of maternal socioeconomic deprivation and living environment on newborn bloodspot 25-hydroxyvitamin D levels.Frontiers in endocrinology · 2022Article
- Maternal Vitamin D Levels During Pregnancy and Offspring Autism Spectrum Disorder.Biological psychiatry · 2021Article
- Maternal Vitamin D Levels and the Risk of Offspring Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Article
- Smoking during pregnancy reduces vitamin D levels in a Finnish birth register cohort.Public health nutrition · 2020Article
- Association of first trimester maternal vitamin D, ferritin and hemoglobin level with third trimester fetal biometry: result from cohort study on vitamin D status and its impact during pregnancy and childhood in Indonesia.BMC pregnancy and childbirth · 2019Article
- Identifying eating habits in Finnish children: a cross-sectional study.BMC public health · 2019Article
- Review
- Food and Nutrient Intake and Nutrient Sources in 1-Year-Old Infants in Finland: A Cross-Sectional Analysis.Nutrients · 2017Article
- Reply to Letter to the Editor to Maternal vitamin D status during pregnancy in Europe: the two sides of the story.European journal of nutrition · 2017Article
- Maternal vitamin D status during pregnancy in Europe: the two sides of the story.European journal of nutrition · 2017Article
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe objectives of this cross-sectional study were to define maternal and umbilical cord blood (UCB) 25-hydroxyvitamin D (25(OH)D) to characterize maternal factors modifying 25(OH)D during pregnancy and predict UCB 25(OH)D in two subgroups with Declined [Δ25(OH)D <0 nmol/l] and Increased [Δ25(OH)D >0 nmol/l] 25(OH)D concentration.
methodsA complete dataset was available from 584 women. 25(OH)D was determined at gestational weeks 6-13 and in UCB. Baseline characteristics were collected retrospectively using questionnaires. Δ25(OH)D was calculated as UCB 25(OH)D-early pregnancy 25(OH)D. Dietary patterns were generated with principal component analysis. Multivariate regression models were applied.
resultsVitamin D deficiency was scarce, since only 1% had 25(OH)D concentration <50 nmol/l both in early pregnancy and in UCB. Shared positive predictors of UCB 25(OH)D in the subgroups of Declined and Increased, were early pregnancy 25(OH)D (P < 0.001) and supplemental vitamin D intake (P < 0.04). For the Increased subgroup summer season at delivery (P = 0.001) and "sandwich and dairy" dietary pattern characterized with frequent consumption of vitamin D fortified margarine and milk products (P = 0.009) were positive predictors of UCB 25(OH)D. Physical activity (P = 0.041) and maternal education (P = 0.004) were additional positive predictors in the Declined group
conclusionsMaternal and newborn vitamin D status was sufficient, thus public health policies in Finland have been successful. The key modifiable maternal determinants for 25(OH)D during pregnancy, and of the newborn, were supplemental vitamin D intake, frequent consumption of vitamin D fortified foods, and physical activity.
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