Evidence map›Paper›PMID 28255614›Full record

ArticleIntensive care medicine2017

What endpoints should be used for clinical studies in acute kidney injury?

John A Kellum, Alexander Zarbock, Mitra K Nadim

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03534141 naterminatednot on this mapstarted 2018, after this paper: background citation

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation (MHALT) Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2018 to 2023Enrolled175ConditionsCirrhosis, End Stage Liver Disease, Acute Kidney Injury, Liver TransplantArmsEsophageal cooling/warming device, Mild hypothermia, Normothermia
NCT04901169 phase2 / phase3active not recruitingnot on this mapstarted 2022, after this paper: background citation

Angiotensin II in Liver Transplantation (AngLT-1): A Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2022 to 2027Enrolled50ConditionsLiver Transplant, Complications, VasoplegiaArmsAngiotensin II, Saline
NCT06299215 completednot on this mapstarted 2024, after this paper: background citation

Factors Associated With the Prognosis of Patients Admitted to for Acute Obstructive Pyelonephritis

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2024 to 2025Enrolled575ConditionsPyelonephritis, Prognostic
3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Balanced Crystalloids versus Saline in Sepsis. A Secondary Analysis of the SMART Clinical Trial.American journal of respiratory and critical care medicine · 2019
    Trial
  2. Balanced Crystalloids versus Saline in Critically Ill Adults.The New England journal of medicine · 2018
    Trial
  3. Trial
  4. Article
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  7. Review
  8. Protocol summary and statistical analysis plan for the sodium bicarbonate for metabolic acidosis in the intensive care unit (SODa-BIC) trial.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025
    Article
  9. Article
  10. Article
  11. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

John A KellumCenter for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, 604, Scaife Hall, 3550 Terrace Street, Pittsburgh, PA, 15261, USA. kellumja@upmc.edu.
Alexander ZarbockDepartment of Anaesthesiology, Intensive Care Medicine and Pain Medicine, University Hospital Münster, Münster, Germany.
Mitra K NadimDivision of Nephrology and Hypertension, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acute Kidney InjuryClinical Studies as TopicEndpoint DeterminationBiomarkersDisease ProgressionHumansQuality of LifeRegistriesRisk FactorsTreatment OutcomeBiomarkers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.