Evidence map›Paper›PMID 28255465›Full record

ArticleNeural plasticity2017

Altered Brain Functional Activity in Infants with Congenital Bilateral Severe Sensorineural Hearing Loss: A Resting-State Functional MRI Study under Sedation.

Shuang Xia, TianBin Song, Jing Che, Qiang Li, Chao Chai, Meizhu Zheng, Wen Shen

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shuang XiaDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.ORCID 0000-0003-1626-6383
TianBin SongDepartment of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.ORCID 0000-0002-9646-6539
Jing CheDepartment of Ultrasound, Aerospace Central Hospital, Beijing 100049, China.
Qiang LiSchool of Law and Politics, Tianjin University of Technology, Tianjin 300384, China.
Chao ChaiDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Meizhu ZhengDepartment of Radiology, Tianjin Third Central Hospital, Tianjin 300172, China.
Wen ShenDepartment of Radiology, Tianjin First Central Hospital, Tianjin 300192, China.
Tianjin First Center Hospital · CNAerospace Center Hospital · CNCapital Medical University · CNTianjin Third Central Hospital · CNTianjin University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early hearing deprivation could affect the development of auditory, language, and vision ability. Insufficient or no stimulation of the auditory cortex during the sensitive periods of plasticity could affect the function of hearing, language, and vision development. Twenty-three infants with congenital severe sensorineural hearing loss (CSSHL) and 17 age and sex matched normal hearing subjects were recruited. The amplitude of low frequency fluctuations (ALFF) and regional homogeneity (ReHo) of the auditory, language, and vision related brain areas were compared between deaf infants and normal subjects. Compared with normal hearing subjects, decreased ALFF and ReHo were observed in auditory and language-related cortex. Increased ALFF and ReHo were observed in vision related cortex, which suggest that hearing and language function were impaired and vision function was enhanced due to the loss of hearing. ALFF of left Brodmann area 45 (BA45) was negatively correlated with deaf duration in infants with CSSHL. ALFF of right BA39 was positively correlated with deaf duration in infants with CSSHL. In conclusion, ALFF and ReHo can reflect the abnormal brain function in language, auditory, and visual information processing in infants with CSSHL. This demonstrates that the development of auditory, language, and vision processing function has been affected by congenital severe sensorineural hearing loss before 4 years of age.

Indexed as

BrainBrain MappingChild, PreschoolFemaleFrontal LobeHearing Loss, SensorineuralHumansInfantLanguageMagnetic Resonance ImagingMaleOccipital LobeProcedural SedationTemporal Lobe

Identifiers

PMID28255465
PMCPMC5309418
OpenAlexW2584472987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.