ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2017
Association between obesity and heart rate variability indices: an intuition toward cardiac autonomic alteration - a risk of CVD.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04029532 (Factors Associated With Obesity in Adult Women), which is not on this map. Cited by 91 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Factors Associated With Obesity in Adult Women: Respiratory Exchange Ratio, Heart Rate Variation and Body Image
Who cites it
91 citing papers in PubMed, 3 syntheses or guidelines pooled it, 186 citations in OpenAlex.
- Exploring heart rate variability in polycystic ovary syndrome: implications for cardiovascular health: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Association between non-acute Traumatic Injury (TI) and Heart Rate Variability (HRV) in adults: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Heart rate variability in type 2 diabetes mellitus: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Effectiveness of Early Versus Late Time-Restricted Eating Combined with Physical Activity in Overweight or Obese Women.Nutrients · 2025Trial
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- Risk Factors Associated with Cardiac Autonomic Modulation in Obese Individuals.Journal of obesity · 2020Trial
- Effect of Violent Video Games on Heart Rate Variability with Different Durations among Nonhabitual Young Adults: A Quasi-experimental Study.Annals of African medicine · 2026Article
- Morphological Correlates of Suppressed Autonomic Modulation: A Machine Learning Approach to Identifying Vagal Impairment Phenotypes in Women.Journal of functional morphology and kinesiology · 2026Article
- Effects of BMI and Anticoagulant/Antiplatelet Therapy on the Severity of Gastrointestinal Bleeding.Medicina (Kaunas, Lithuania) · 2026Article
- Higher body-mass index modifies time-resolved maternal autonomic cardiac-uterine coupling during the first stage of human labour.Experimental physiology · 2026Article
- Association of Severe Obesity, Hypertension, and Physical Activity with 24 h Heart Rate Variability in Adults.Journal of cardiovascular development and disease · 2026Article
- Autonomic Modulation and Body Composition in Educators: Physiological Associations in the Workplace Context.Brain and behavior · 2026Article
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- Senolytic treatment with dasatinib and quercetin selectively improves cardiac autonomic balance in obesity.GeroScience · 2026Article
- Complexity-Aware Artificial Intelligence in Metabolic Bariatric Surgery: Beyond Static Risk Prediction.Obesity surgery · 2026Review
- A larger amount of palatable food is needed to provide stress relief during Western diet-induced obesity.Physiology & behavior · 2026Article
- The Effects of Sleeve Gastrectomy on Blood Pressure, Blood Pressure Variability, and Autonomic Functions in Severely Obese Patients Without Diabetes or Hypertension.Journal of clinical medicine · 2026Article
- Associations between body composition and autonomic cardiorespiratory modulation in young adults.Physiological reports · 2026Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObese people have a higher prevalence of cardiovascular disease, which is supposed to be due to autonomic dysfunction and/or metabolic disorder. The alterations in cardiac autonomic functions bring out the changes in the heart rate variability (HRV) indicators, an assessing tool for cardiac autonomic conditions.
objectiveTo compare the cardiac autonomic activity between obese and normal weight adults and find out the highest association between the indices of HRV and obesity.
methodsThe study was conducted in 30 adult obese persons (body mass index [BMI] >30 kg/m
resultsIn the obese group, there was a significant increase in the mean heart rate, whereas the HRV parasympathetic indicators were less (eg, root mean square of differences of successive RR intervals [28.75 {16.72-38.35} vs 41.55 {30.6-56.75} ms,
conclusionIncreased WHR, by far an indicator of visceral adiposity, was strongly associated with reduced cardiac parasympathetic and increased sympathetic activity in obese individuals defined by BMI. However, BMI itself has a weak relationship with HRV cardiac autonomic markers. Thus, even with a slight increase in WHR in an individual, there could be a greater risk of cardiovascular morbidity and mortality brought about by cardiac autonomic alterations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.