Evidence map›Paper›PMID 28255095›Full record

ArticleBMJ open2017

Acceptability of the Cytosponge procedure for detecting Barrett's oesophagus: a qualitative study.

Madeleine Freeman, Judith Offman, Fiona M Walter, Peter Sasieni, Samuel G Smith

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Barriers and Enablers to Capsule Sponge Screening Among People With Heartburn: A Community-Based Qualitative Study in the UK.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
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  16. Article
  17. Novel Screening Tests for Barrett's Esophagus.Current gastroenterology reports · 2019
    Review
  18. Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019
    Article
  19. A crosssectional analysis of Facebook comments to study public perception of a new diagnostic test called the Cytosponge.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2019
    Article
  20. Barrett's esophagus: novel strategies for screening and surveillance.Therapeutic advances in chronic disease · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Madeleine FreemanWolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
Judith OffmanWolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.ORCID 0000-0001-5604-1635
Fiona M WalterPrimary Care Unit, Department of Public Health & Primary Care, University of Cambridge, Cambridge, UK.ORCID 0000-0002-7191-6476
Peter SasieniWolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
Samuel G SmithWolfson Institute of Preventive Medicine, Queen Mary University of London, London, UK.
Queen Mary University of London · GBUniversity of Cambridge · GBUniversity of Leeds · GB

Funding

Cancer Research UK 16892Cancer Research UK 16893Cancer Research UK 17965Cancer Research UK C42785/A17965Cancer Research UK C8162/A16892
6 · The paper itself

Abstract

objectiveTo investigate the acceptability of the Cytosponge, a novel sampling device to detect Barrett's oesophagus (BE), a precursor to oesophageal adenocarcinoma (EAC), among people with risk factors for this condition.

designA qualitative study using semistructured interviews and focus group discussions. Data were explored by three researchers using thematic analysis.

settingCommunity setting in London, UK.

participantsA recruitment company identified 33 adults (17 men, 16 women) aged 50-69 years with gastro-oesophageal reflux disease (GERD), a risk factor for BE. The majority of participants were white British (73%). The focus groups were stratified by gender and education. 10 individuals were interviewed and 23 participated in four focus groups.

results3 key themes emerged from the data: the anticipated physical experience, preferences for the content of information materials and comparisons with the current gold-standard test. Overall acceptability was high, but there was initial concern about the physical experience of taking the test, including swallowing and extracting the Cytosponge. These worries were reduced after handling the device and a video demonstration of the procedure. Knowledge of the relationship between GERD, BE and EAC was poor, and some suggested they would prefer not to know about the link when being offered the Cytosponge. Participants perceived the Cytosponge to be more comfortable, practical and economical than endoscopy.

conclusionsThese qualitative data suggest the Cytosponge was acceptable to the majority of participants with risk factors for BE, and could be used as a first-line test to investigate GERD symptoms. Concerns about the physical experience of the test were alleviated through multimedia resources. The development of patient information materials is an important next step to ensuring patients are adequately informed and reassured about the procedure. Patient stakeholders should be involved in this process to ensure their concerns and preferences are considered. TRIAL REGISTRATION NUMBER: ISRCTN68382401; pre-results.

Indexed as

Patient Acceptance of Health CareAgedBarrett EsophagusDiagnostic Techniques, Digestive SystemEndoscopyFemaleFocus GroupsGastroesophageal RefluxHumansInterviews as TopicLondonMaleMiddle AgedPathologyQualitative ResearchRisk FactorsAcceptabilityBarrett’s oesophagusCytospongeDiagnosisOesophageal adenocarcinomaQUALITATIVE RESEARCH

Identifiers

PMID28255095
PMCPMC5353314
OpenAlexW2594592826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.