Evidence map›Paper›PMID 28255086›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Mechanisms of the deep, slow-wave, sleep-related increase of upper airway muscle tone in healthy humans.

Amelia Hicks, Jennifer M Cori, Amy S Jordan, Christian L Nicholas, Leszek Kubin, John G Semmler, Atul Malhotra, David G P McSharry, John A Trinder

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Cardioventilatory Control in Preterm-born Children and the Risk of Obstructive Sleep Apnea.American journal of respiratory and critical care medicine · 2018
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Amelia HicksSchool of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.
Jennifer M CoriSchool of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.
Amy S JordanSchool of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.
Christian L NicholasSchool of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.
Leszek KubinDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
John G SemmlerSchool of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Atul MalhotraDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California at San Diego, San Diego, California; and.
David G P McSharrySchool of Medicine and Medical Science, University College Dublin and Mater Misericordiae University Hospital, Dublin, Ireland.
John A TrinderSchool of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia; johnat@unimelb.edu.au.
University of Melbourne · AUAustralian Psychological Society · AUMater Misericordiae University Hospital · IEUniversity of Adelaide · AUUniversity of California System · USUniversity of Pennsylvania · US

Funding

PREMOTOR CONTROL OF UPPER AIRWAY AND REM SLEEP ATONIAR01HL047600 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KUBIN, LESZEK K · 1992 to 2018
$5.6M
Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Assessment of Upper Airway Mechanics Using Newer Electromyographic TechniquesK24HL132105 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2016 to 2020
$611k
NHLBI NIH HHS K24 HL132105NHLBI NIH HHS R01 HL047600NHLBI NIH HHS R01 HL085188NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

Upper airway muscle activity is reportedly elevated during slow-wave sleep (SWS) when compared with lighter sleep stages. To uncover the possible mechanisms underlying this elevation, we explored the correlation between different indices of central and reflex inspiratory drive, such as the changes in airway pressure and end-expiratory CO

Indexed as

AdultAirway ResistanceCarbon DioxideElectromyographyHumansMaleMuscle, SkeletalMuscle TonusPolysomnographyPressureReflexRespirationRespiratory SystemSleep StagesYoung AdultCarbon Dioxidegenioglossusnon-rapid eye movement sleepslow-wave sleeptensor palatiniupper airway muscles

Identifiers

PMID28255086
PMCPMC6157479
OpenAlexW2592972642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.