Evidence map›Paper›PMID 28255023›Full record

ArticleHaematologica2017

The clinical and molecular diversity of mast cell leukemia with or without associated hematologic neoplasm.

Mohamad Jawhar, Juliana Schwaab, Manja Meggendorfer, Nicole Naumann, Hans-Peter Horny, Karl Sotlar, Torsten Haferlach, Karla Schmitt, Alice Fabarius, Peter Valent and 4 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 95 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Diagnosing Systemic Mastocytosis: State of the Art.International journal of laboratory hematology · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Mastocytosis demystified.Hematology. American Society of Hematology. Education Program · 2023
    Review
  17. Aleukemic Variant of Mast Cell Leukemia with del (7)(q31): Rare Case Report of an Elderly Chinese ManTurkish journal of haematology : official journal of Turkish Society of Haematology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Mohamad JawharDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Juliana SchwaabDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Manja MeggendorferMunich Leukemia Laboratory, Germany.
Nicole NaumannDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Hans-Peter HornyInstitute of Pathology, Ludwig-Maximilians-University, Munich, Germany.
Karl SotlarUniversity Institute of Pathology, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.
Torsten HaferlachMunich Leukemia Laboratory, Germany.
Karla SchmittDepartment of Hematology and Oncology, University Hospital Aachen, Germany.
Alice FabariusDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Peter ValentDepartment of Internal Medicine I, Division of Hematology and Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
Wolf-Karsten HofmannDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Nicholas C P CrossWessex Regional Genetics Laboratory, Salisbury, UK.
Georgia MetzgerothDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany.
Andreas ReiterDepartment of Hematology and Oncology, University Medical Centre Mannheim, Germany andreas.reiter@medma.uni-heidelberg.de.
University Hospital Heidelberg · DEHeidelberg University · DEMunich Leukemia Laboratory (Germany) · DELudwig Boltzmann Cluster for Cardiovascular Research · ATLudwig-Maximilians-Universität München · DEParacelsus Medical University · ATUniversitätsklinikum Aachen · DEUniversity Medical Centre Mannheim · DEUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cell leukemia is a rare variant of advanced systemic mastocytosis characterized by at least 20% of mast cells in a bone marrow smear. We evaluated clinical and molecular characteristics of 28 patients with (n=20, 71%) or without an associated hematologic neoplasm.

Indexed as

Disease ProgressionMutationCladribineCore Binding Factor Alpha 2 SubunitFemaleHematologic NeoplasmsHumansLeukemia, Mast-CellMaleMastocytosis, SystemicMiddle AgedPrognosisRepressor ProteinsSerine-Arginine Splicing FactorsStaurosporineSurvival RateASXL1 protein, humanCladribineCore Binding Factor Alpha 2 SubunitmidostaurinRepressor ProteinsRUNX1 protein, humanSerine-Arginine Splicing FactorsSRSF2 protein, humanStaurosporine

Identifiers

PMID28255023
PMCPMC5451335
OpenAlexW2592769270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.