Evidence map›Paper›PMID 28255007›Full record

ArticleDevelopment (Cambridge, England)2017

The human chorion contains definitive hematopoietic stem cells from the fifteenth week of gestation.

Marcus O Muench, Mirhan Kapidzic, Matthew Gormley, Alan G Gutierrez, Kathryn L Ponder, Marina E Fomin, Ashley I Beyer, Haley Stolp, Zhongxia Qi, Susan J Fisher and 1 more

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Silencing P38 MAPK reduces cellular senescence in human fetal chorion trophoblast cells.American journal of reproductive immunology (New York, N.Y. : 1989) · 2023
    Article
  9. Clonal Hematopoiesis: Role in Hematologic and Non-Hematologic Malignancies.Mediterranean journal of hematology and infectious diseases · 2022
    Review
  10. Article
  11. Growing and aging of hematopoietic stem cells.World journal of stem cells · 2021
    Review
  12. Article
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marcus O MuenchBlood Systems Research Institute, San Francisco, CA 94118, USA.ORCID 0000-0001-8946-6605
Mirhan KapidzicThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.
Matthew GormleyThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-2042-1534
Alan G GutierrezThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.ORCID 0000-0002-8567-9598
Kathryn L PonderThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.
Marina E FominBlood Systems Research Institute, San Francisco, CA 94118, USA.ORCID 0000-0002-1573-8126
Ashley I BeyerBlood Systems Research Institute, San Francisco, CA 94118, USA.ORCID 0000-0002-9306-3515
Haley StolpThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-1635-894X
Zhongxia QiDepartment of Laboratory Medicine, Clinical Cytogenetics Laboratory, University of California, San Francisco, CA 94107, USA.
Susan J FisherThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA.
Alicia BárcenaThe Ely and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA Alicia.Barcena@ucsf.edu.ORCID 0000-0003-3463-0628

Funding

Reprogramming iPS Cells with Exogenous and Endogenous Transcription Factor GenesP01DK088760 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRUENERT, DIETER C · 2011 to 2015
$6.5M
Graduate Training Program in Neonatal-Perinatal Translational ResearchT32HD071860 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROWITCH, DAVID H · 2012 to 2016
$969k
HCMV infection of human placental trophoblast and hematopoietic progenitorsR56AI101130 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PEREIRA, LENORE PALMA · 2012 to 2012
$546k
The human placenta as a novel source of hematopoietic stem cellsR21HD055328 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BARCENA, ALICIA LIZCANO · 2008 to 2009
$433k
NIAID NIH HHS R56 AI101130NICHD NIH HHS R21 HD055328NICHD NIH HHS T32 HD071860NIDDK NIH HHS P01 DK088760
6 · The paper itself

Abstract

We examined the contribution of the fetal membranes, amnion and chorion, to human embryonic and fetal hematopoiesis. A population of cells displaying a hematopoietic progenitor phenotype (CD34

Indexed as

AnimalsAntigens, CDCell Adhesion MoleculesCell CountCell LineageChorionChorionic VilliCollagenasesFemaleFetusHematopoietic Stem CellsHumansIntegrin beta1Mice, SCIDPhenotypePregnancyAntigens, CDCell Adhesion MoleculesCollagenasesIntegrin beta1Receptors, ChemokineTrypsinChorionExtraembryonic developmentHematopoietic developmentHuman hematopoietic stem cells

Identifiers

PMID28255007
PMCPMC5399660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.