Evidence map›Paper›PMID 28254796›Full record

ArticleCirculation research2017

A New Role for the ER Unfolded Protein Response Mediator ATF6: Induction of a Generalized Antioxidant Program.

Wendy M McKimpson, Richard N Kitsis

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Wendy M McKimpsonFrom the Department of Medicine (W.M.M., R.N.K.), Department of Cell Biology (W.M.M., R.N.K.), Wilf Family Cardiovascular Research Center (W.M.M., R.N.K.), Einstein-Mount Sinai Diabetes Research Center (R.N.K.), and Albert Einstein Cancer Center (R.N.K.), Albert Einstein College of Medicine, Bronx, NY.
Richard N KitsisFrom the Department of Medicine (W.M.M., R.N.K.), Department of Cell Biology (W.M.M., R.N.K.), Wilf Family Cardiovascular Research Center (W.M.M., R.N.K.), Einstein-Mount Sinai Diabetes Research Center (R.N.K.), and Albert Einstein Cancer Center (R.N.K.), Albert Einstein College of Medicine, Bronx, NY. richard.kitsis@einstein.yu.edu.

Funding

TRAINING PROGRAM IN CELLULAR &MOLEC. BIOLOGY &GENETICST32GM007491 · NIGMS · YESHIVA UNIVERSITY · PI QUERY, CHARLES C · 1985 to 2021
$17.0M
POSTDOCTORAL TRAINING IN ARTERIOSCLEROSIS RESEARCHT32HL007343 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HENRY N GINSBERG, Muredach P Reilly · 1985 to 2026
$12.7M
A new molecular pathway for diabetic cardiomyopathyR01HL130861 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KITSIS, RICHARD N, YOSHIOKA, JUN · 2016 to 2019
$2.4M
Linking cell death and mitochondrial quality control mechanisms in heart diseaseR01HL128071 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI DORN, GERALD W., KITSIS, RICHARD N · 2015 to 2018
$2.1M
NHLBI NIH HHS R01 HL128071NHLBI NIH HHS R01 HL130861NHLBI NIH HHS T32 HL007343NIGMS NIH HHS T32 GM007491
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntioxidantsMyocardial Reperfusion InjuryActivating Transcription Factor 6HumansOxidative StressSignal TransductionUnfolded Protein ResponseActivating Transcription Factor 6AntioxidantsATF6 protein, humanEditorialsendoplasmic reticulumoxidative stressreperfusion injuryselenoproteinsunfolded protein response

Identifiers

PMID28254796
PMCPMC5345692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.