Evidence map›Paper›PMID 28254775›Full record

ArticleMolecular & cellular proteomics : MCP2017

Global Analysis of SUMO-Binding Proteins Identifies SUMOylation as a Key Regulator of the INO80 Chromatin Remodeling Complex.

Eric Cox, Woochang Hwang, Ijeoma Uzoma, Jianfei Hu, Catherine M Guzzo, Junseop Jeong, Michael J Matunis, Jiang Qian, Heng Zhu, Seth Blackshaw

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Long non-coding RNAs: the tentacles of chromatin remodeler complexes.Cellular and molecular life sciences : CMLS · 2021
    Review
  14. Article
  15. Article
  16. Regulation of axon repulsion by MAX-1 SUMOylation and AP-3.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Eric CoxFrom the ‡Biochemistry, Cellular and Molecular Biology Graduate Program.
Woochang Hwang‖Wilmer Eye Institute.
Ijeoma Uzoma¶Department of Pharmacology and Molecular Sciences.
Jianfei Hu‖Wilmer Eye Institute.
Catherine M Guzzo**Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Junseop Jeong¶Department of Pharmacology and Molecular Sciences.
Michael J Matunis**Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Jiang Qian‖Wilmer Eye Institute.
Heng Zhu¶Department of Pharmacology and Molecular Sciences.
Seth Blackshaw§Solomon H. Snyder Department of Neuroscience, sblack@jhmi.edu.
National Eye Institute · USHigh Throughput Biology (United States) · USJohns Hopkins University · USUniversity of Maryland, Baltimore · USJohns Hopkins Medicine · US

Funding

TCP5: ACTIVE SITE LABELING REAGENT FOR ACETYLTRANSFERASESU54RR020839 · NCRR · JOHNS HOPKINS UNIVERSITY · PI BOEKE, JEF D · 2004 to 2011
$27.4M
Regulation and Function of SUMO Protein Modification -Equipment SupplementR01GM060980 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI MATUNIS, MICHAEL J. · 2000 to 2023
$7.1M
The role of PIAS3 in retinal developmentR01EY017015 · NEI · JOHNS HOPKINS UNIVERSITY · PI BLACKSHAW, SETH · 2007 to 2017
$4.2M
NCRR NIH HHS U54 RR020839NEI NIH HHS R01 EY017015NIGMS NIH HHS R01 GM060980
6 · The paper itself

Abstract

SUMOylation is a critical regulator of a broad range of cellular processes, and is thought to do so in part by modulation of protein interaction. To comprehensively identify human proteins whose interaction is modulated by SUMOylation, we developed an

Indexed as

Chromatin Assembly and DisassemblySumoylationAmino Acid MotifsAmino Acid SequenceATPases Associated with Diverse Cellular ActivitiesBasic Helix-Loop-Helix ProteinsDNA-Binding ProteinsDNA HelicasesGene OntologyHumansLysineMolecular ChaperonesProtein Array AnalysisProtein BindingProtein DomainsProtein Inhibitors of Activated STATATPases Associated with Diverse Cellular ActivitiesBasic Helix-Loop-Helix ProteinsDNA-Binding ProteinsDNA HelicasesINO80 protein, humanLysineMolecular ChaperonesPIAS1 protein, humanPIAS3 protein, humanProtein Inhibitors of Activated STATProteomeSmall Ubiquitin-Related Modifier ProteinsTFPT protein, human

Identifiers

PMID28254775
PMCPMC5417823
OpenAlexW2593321113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.