ArticleArchives of physical medicine and rehabilitation2017
Anticipatory Postural Adjustment During Self-Initiated, Cued, and Compensatory Stepping in Healthy Older Adults and Patients With Parkinson Disease.
Article in Archives of physical medicine and rehabilitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Effects of Oral Levodopa on Balance in People with Idiopathic Parkinson's Disease.Journal of Parkinson's disease · 2023Pooled it
- Surface electromyographic profiles during gait initiation in people with Parkinson's disease: The effects of external sensory cueing.Journal of Parkinson's disease · 2025Article
- Motor planning stage of gait initiation: effects of aging, Parkinson's disease, and associations with cognitive function.Experimental brain research · 2025Article
- Sensorimotor perturbation-induced cortical responses by a novel PES system: analysis of the N1 component in healthy adults and Parkinson's disease.Frontiers in human neuroscience · 2025Article
- Quantitative analysis of gait parameters in Parkinson's disease and the clinical significance.Frontiers in neurology · 2025Article
- Standing on Elevated Platform Changes Postural Reactive Responses during Arm Movement.Brain sciences · 2024Article
- Associating white matter microstructural integrity and improvements in reactive stepping in people with Parkinson's Disease.Brain imaging and behavior · 2024Article
- Towards a better understanding of anticipatory postural adjustments in people with Parkinson's disease.PloS one · 2024Article
- Does Impaired Plantar Cutaneous Vibration Perception Contribute to Axial Motor Symptoms in Parkinson's Disease? Effects of Medication and Subthalamic Nucleus Deep Brain Stimulation.Brain sciences · 2023Article
- Article
- Gait Initiation Impairment in Patients with Parkinson's Disease and Freezing of Gait.Bioengineering (Basel, Switzerland) · 2022Article
- Using kinematics to re-define the pull test as a quantitative biomarker of the postural response in normal pressure hydrocephalus patients.Experimental brain research · 2022Article
- Discussion of Research Priorities for Gait Disorders in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2022Review
- Characterization of Anticipatory Postural Adjustments in Lateral Stepping: Impact of Footwear and Lower Limb Preference.Sensors (Basel, Switzerland) · 2021Article
- Impact of social and mobility restrictions in Parkinson's disease during COVID-19 lockdown.BMC neurology · 2021Article
- Variability in the Center of Mass State During Initiation of Accurate Forward Step Aimed at Targets of Different Sizes.Frontiers in sports and active living · 2021Article
- Rate of torque development and striatal shape in individuals with prodromal Huntington's disease.Scientific reports · 2020Article
- Cueing Paradigms to Improve Gait and Posture in Parkinson's Disease: A Narrative Review.Sensors (Basel, Switzerland) · 2019Review
- How to Select Balance Measures Sensitive to Parkinson's Disease from Body-Worn Inertial Sensors-Separating the Trees from the Forest.Sensors (Basel, Switzerland) · 2019Article
- Reproducibility and responsiveness of gait initiation in Parkinson's disease.Journal of biomechanics · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
objectiveTo characterize anticipatory postural adjustments (APAs) across a variety of step initiation tasks in people with Parkinson disease (PD) and healthy subjects.
designCross-sectional study. Step initiation was analyzed during self-initiated gait, perceptual cued gait, and compensatory forward stepping after platform perturbation. People with PD were assessed on and off levodopa.
settingUniversity research laboratory.
participantsPeople (N=31) with PD (n=19) and healthy aged-matched subjects (n=12).
interventionsNot applicable.
main outcome measuresMediolateral (ML) size of APAs (calculated from center of pressure recordings), step kinematics, and body alignment.
resultsWith respect to self-initiated gait, the ML size of APAs was significantly larger during the cued condition and significantly smaller during the compensatory condition (P<.001). Healthy subjects and patients with PD did not differ in body alignment during the stance phase prior to stepping. No significant group effect was found for ML size of APAs between healthy subjects and patients with PD. However, the reduction in APA size from cued to compensatory stepping was significantly less pronounced in PD off medication compared with healthy subjects, as indicated by a significant group by condition interaction effect (P<.01). No significant differences were found comparing patients with PD on and off medications.
conclusionsSpecific stepping conditions had a significant effect on the preparation and execution of step initiation. Therefore, APA size should be interpreted with respect to the specific stepping condition. Across-task changes in people with PD were less pronounced compared with healthy subjects. Antiparkinsonian medication did not significantly improve step initiation in this mildly affected PD cohort.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.