Evidence map›Paper›PMID 28254565›Full record

ArticleUltrasonics2017

In vitro ultrasound experiments: Standing wave and multiple reflections influence on the outcome.

Wojciech Secomski, Krzysztof Bilmin, Tamara Kujawska, Andrzej Nowicki, Paweł Grieb, Peter A Lewin

Abstract read
In one paragraph

Article in Ultrasonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Silent Death by Sound: CInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Development of Low Frequency (20-100 kHz) Clinically Viable Ultrasound Applicator for Chronic Wound Treatment.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wojciech SecomskiInstitute of Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5b, 02-106 Warszawa, Poland. Electronic address: Wojciech.Secomski@ippt.pan.pl.
Krzysztof BilminMossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warszawa, Poland.
Tamara KujawskaInstitute of Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5b, 02-106 Warszawa, Poland.
Andrzej NowickiInstitute of Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5b, 02-106 Warszawa, Poland.
Paweł GriebMossakowski Medical Research Centre, Polish Academy of Sciences, Pawińskiego 5, 02-106 Warszawa, Poland.
Peter A LewinSchool of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

Funding

Enhanced ultrasound treatment of chronic wounds with monitoring of healing and quality of life outcomesR01NR015995 · NINR · DREXEL UNIVERSITY · PI LEWIN, PETER A. · 2016 to 2020
$3.4M
NINR NIH HHS R01 NR015995
6 · The paper itself

Abstract

The purpose of this work was to determine the influence of standing waves and possible multiple reflections under the conditions often encountered in examining the effects of ultrasound exposure on the cell cultures in vitro. More specifically, the goal was to quantitatively ascertain the influence of ultrasound exposure under free field (FF) and standing waves (SW) and multiple reflections (MR) conditions (SWMR) on the biological endpoint (50% cell necrosis). Such information would help in designing the experiments, in which the geometry of the container with biological tissue may prevent FF conditions to be established and in which the ultrasound generated temperature elevation is undesirable. This goal was accomplished by performing systematic, side-by-side experiments in vitro with C6 rat glioma cancer cells using 12 well and 96 well plates. It was determined that to obtain 50% of cell viability using the 12 well plates, the spatial average, temporal average (I

Indexed as

AnimalsApoptosisCell Line, TumorEquipment DesignGliomaIn Vitro TechniquesPressureRatsSonicationTemperatureTransducersTumor Cells, CulturedUltrasonic TherapyAnticancer therapyC6 gliomaSonodynamic therapyStanding waveUltrasound bio-effectsUltrasound intensityUltrasound pressure

Identifiers

PMID28254565
PMCPMC5503701

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.