Evidence map›Paper›PMID 28254203›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2017

Factors associated with poor controller medication use in children with high asthma emergency department use.

Arlene Butz, Tricia Morphew, Cassia Lewis-Land, Joan Kub, Melissa Bellin, Jean Ogborn, Shawna S Mudd, Mary Elizabeth Bollinger, Mona Tsoukleris

Registry-linked trialAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01981564 (Asthma Express Intervention to Bridge Emergency to Primary Care for High Risk Children With Asthma), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01981564 nacompletednot on this map

Asthma Express Intervention to Bridge Emergency to Primary Care for High Risk Children With Asthma

TypeinterventionalSponsorJohns Hopkins UniversityRan2013 to 2018Enrolled222ConditionsAsthmaArmsAsthma Express Intervention, Standard Asthma Education Control Group
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Implementation of Coach McLungsBMC medical informatics and decision making · 2022
    Trial
  2. Trial
  3. Characteristics of inner-city children with life-threatening asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Trial
  4. Very Poorly Controlled Asthma in Urban Minority Children: Lessons Learned.The journal of allergy and clinical immunology. In practice
    Trial
  5. Fostering Effective Asthma Self-Management Transfer in High-Risk Children: Gaps and Opportunities for Family Engagement.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Trial
  6. Improving Care of Inner-City Children with Poorly Controlled Asthma: What Mothers Want You to Know.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Trial
  7. Article
  8. Article
  9. Cost barriers to asthma care by health insurance type among children with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2020
    Article
  10. Evaluation of MOS social support in low-income caregivers of African American children with poorly controlled asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arlene ButzDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland; School of Nursing, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: abutz@jhmi.edu.
Tricia MorphewMorphew Consulting LLC, Bothell, Washington.
Cassia Lewis-LandDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Joan KubSchool of Nursing, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Melissa BellinSchool of Social Work, University of Maryland, Baltimore, Maryland.
Jean OgbornDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Shawna S MuddSchool of Nursing, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Mary Elizabeth BollingerDepartment of Pediatric Pulmonary and Allergy, School of Medicine, University of Maryland, Baltimore, Maryland.
Mona TsouklerisSchool of Pharmacy, University of Maryland, Baltimore, Maryland.

Funding

Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Asthma Express: Bridging Emergency to Primary Care in Underserved ChildrenR01NR013486 · NINR · JOHNS HOPKINS UNIVERSITY · PI BUTZ, ARLENE MANNS · 2013 to 2017
$2.3M
NCATS NIH HHS UL1 TR000424NINR NIH HHS R01 NR013486
6 · The paper itself

Abstract

backgroundUnderstanding health and social factors associated with controller medication use in children with high-risk asthma may inform disease management in the home and community.

objectiveTo examine health and social factors associated with the Asthma Medication Ratio (AMR), a measure of guideline-based care and controller medication use, in children with persistent asthma and frequent emergency department (ED) use.

methodsStudy questionnaires, serum allergen sensitization, salivary cotinine, and pharmacy record data were collected for 222 children enrolled from August 2013 to February 2016 in a randomized clinical trial that tested the efficacy of an ED- and home-based intervention. Logistic regression was used to examine factors associated with an AMR greater than 0.50, reflecting appropriate controller medication use.

resultsMost children were male (64%), African American (93%), Medicaid insured (93%), and classified as having uncontrolled asthma (44%). Almost half (48%) received non-guideline-based care or low controller medication use based on an AMR less than 0.50. The final regression model predicting an AMR greater than 0.50 indicated that children receiving specialty care (odds ratio [OR], 4.87; 95% confidence interval [CI], 2.06-11.50), caregivers reporting minimal worry about medication adverse effects (OR, 0.50; 95% CI, 0.25-1.00), positive sensitization to ragweed allergen (OR, 3.82; 95% CI, 1.63-8.96), and negative specific IgE for dust mite (OR, 0.33; 95% CI, 0.15-0.76) were significantly associated with achieving an AMR greater than 0.50.

conclusionClinical decision making for high-risk children with asthma may be enhanced by identification of sensitization to environmental allergens, ascertaining caregiver's concerns about controller medication adverse effects and increased referral to specialty care.

trial registrationClinicalTrials.gov Identifier: NCT01981564.

Indexed as

AllergensAnti-Asthmatic AgentsAsthmaCaregiversChildChild, PreschoolCross-Sectional StudiesEmergency Medical ServicesEmergency Service, HospitalEnvironmental ExposureFactor Analysis, StatisticalFemaleHumansMaleMorbidityPatient Acceptance of Health CareAllergensAnti-Asthmatic Agents

Identifiers

PMID28254203
PMCPMC5385291

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.