Evidence map›Paper›PMID 28253403›Full record

ArticleInvestigative ophthalmology & visual science2017

Visualization of Dietary Patterns and Their Associations With Age-Related Macular Degeneration.

Chung-Jung Chiu, Min-Lee Chang, Tricia Li, Gary Gensler, Allen Taylor

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Investigative ophthalmology & visual science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  10. Glycative stress as a cause of macular degeneration.Progress in retinal and eye research · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chung-Jung ChiuJean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States 2Department of Ophthalmology, School of Medicine, Tufts University, Boston, Massachusetts, United States.
Min-Lee ChangJean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States.
Tricia LiChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.
Gary GenslerAge-Related Eye Disease Study Coordinating Center, The Emmes Corporation, Rockville, Maryland, United States.
Allen TaylorJean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, United States 2Department of Ophthalmology, School of Medicine, Tufts University, Boston, Massachusetts, United States.
Tufts University · USBrigham and Women's Hospital · USEmmes (United States) · USJean Mayer Human Nutrition Research Center on Aging · US

Funding

Ubiquitin Function In Eye LensR01EY013250 · NEI · TUFTS UNIVERSITY BOSTON · PI TAYLOR, ALLEN · 2001 to 2012
$4.0M
Ubiquitin function in eye lensR01EY026979 · NEI · TUFTS UNIVERSITY BOSTON · PI TAYLOR, ALLEN · 2016 to 2018
$1.2M
Mechanistically linking AMD, glycemic index and protein homeostasisR01EY021212 · NEI · TUFTS UNIVERSITY BOSTON · PI TAYLOR, ALLEN · 2011 to 2013
$1.2M
Development of a prediction model for advanced age-related macular degenerationR01EY021826 · NEI · TUFTS UNIVERSITY BOSTON · PI CHIU, CHUNG-JUNG · 2011 to 2013
$1.2M
NEI NIH HHS R01 EY013250NEI NIH HHS R01 EY021212NEI NIH HHS R01 EY021826NEI NIH HHS R01 EY026979
6 · The paper itself

Abstract

Purpose: We aimed to visualize the relationship of predominant dietary patterns and their associations with AMD. Methods: A total of 8103 eyes from 4088 participants in the baseline Age-Related Eye Disease Study (AREDS) were classified into three groups: control (n = 2739), early AMD (n = 4599), and advanced AMD (n = 765). Using principle component analysis, two major dietary patterns and eight minor dietary patterns were characterized. Applying logistic regression in our analysis, we related dietary patterns to the prevalence of AMD. Qualitative comparative analysis by operating Boolean algebra and drawing Venn diagrams was used to visualize our findings. Results: In general, the eight minor patterns were subsets or extensions of either one of the two major dietary patterns (Oriental and Western patterns) and consisted of fewer characteristic foods than the two major dietary patterns. Unlike the two major patterns, which were more strongly associated with both early and advanced AMD, none of the eight minors were associated with early AMD and only four minor patterns, including the Steak pattern (odds ratio comparing the highest to lowest quintile of the pattern score = 1.73 [95% confidence interval: 1.24 to 2.41; Ptrend = 0.02]), the Breakfast pattern (0.60 [0.44 to 0.82]; Ptrend = 0.004]), the Caribbean pattern (0.64 [0.47 to 0.89; Ptrend = 0.009]), and the Peanut pattern (0.64 [0.46 to 0.89; Ptrend = 0.03]), were significantly associated with advanced AMD. Our data also suggested several potential beneficial (peanuts, pizza, coffee, and tea) and harmful (salad dressing) foods for AMD. Conclusions: Our data indicate that a diet of various healthy foods may be optimal for reducing AMD risk. The effects of some specific foods in the context of overall diet warrant further study.

Indexed as

Dietary SupplementsAgedFeeding BehaviorFemaleFollow-Up StudiesHumansIncidenceMacular DegenerationMaleMiddle AgedOdds RatioProspective StudiesRisk FactorsTime FactorsUnited States

Identifiers

PMID28253403
PMCPMC5361454
OpenAlexW2593018897

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.