Observational studyPloS one2017
Effect of goal-directed therapy on outcome after esophageal surgery: A quality improvement study.
Observational study in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- The impact of goal-directed fluid therapy on postoperative pulmonary complications in patients undergoing thoracic surgery: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2024Pooled it
- Effect of perioperative goal-directed fluid therapy on postoperative complications after thoracic surgery with one-lung ventilation: a systematic review and meta-analysis.World journal of surgical oncology · 2023Pooled it
- Effects of perioperative goal-directed fluid therapy combined with the application of alpha-1 adrenergic agonists on postoperative outcomes: a systematic review and meta-analysis.BMC anesthesiology · 2018Pooled it
- Institutional modified post esophagectomy care protocol offers improved perioperative outcomes - a single-center propensity score matched analysis.World journal of surgical oncology · 2026Article
- Safety and feasibility of jejunostomy on elderly patients undergoing minimally invasive esophagectomy.Journal of cardiothoracic surgery · 2026Article
- Article
- Review
- Impact of fluid balance and opioid-sparing anesthesia within enchanced recovery pathway on postoperative morbidity after transthoracic esophagectomy for cancer.Frontiers in medicine · 2024Article
- Review
- The effect of compliance with a perioperative goal-directed therapy protocol on outcomes after high-risk surgery: a before-after study.Journal of clinical monitoring and computing · 2021Article
- Peri-operative approach to esophagectomy: a narrative review from the anesthesiological standpoint.Journal of thoracic disease · 2021Review
- Comparison of Goal-Directed Fluid Therapy using LiDCOrapid System with Regular Fluid Therapy in Patients Undergoing Spine Surgery as a Randomised Clinical Trial.Romanian journal of anaesthesia and intensive care · 2021Article
- Anastomotic leakage after esophagectomy for esophageal cancer: definitions, diagnostics, and treatment.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2021Review
- Stroke Volume Variation-Guided Goal-Directed Fluid Therapy Did Not Significantly Reduce the Incidence of Early Postoperative Complications in Elderly Patients Undergoing Minimally Invasive Esophagectomy: A Randomized Controlled Trial.Frontiers in surgery · 2021Article
- Outcome impact of individualized fluid management during spine surgery: a before-after prospective comparison study.BMC anesthesiology · 2020Article
- Perioperative fluid dynamics evaluated by bioelectrical impedance analysis predict infectious surgical complications after esophagectomy.BMC surgery · 2019Article
- Lack of impact of nil-per-os (NPO) time on goal-directed fluid delivery in first case versus afternoon case starts: a retrospective cohort study.BMC anesthesiology · 2019Article
- Effect of intraoperative fluid administration on perioperative outcomes in patients undergoing McKeown esophagogastrectomy.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2019Article
- Application of standardized hemodynamic protocols within enhanced recovery after surgery programs to improve outcomes associated with anastomotic leak and conduit necrosis in patients undergoing esophagectomy.Journal of thoracic disease · 2019Review
- Proper volume management during anesthesia for esophageal resection.Journal of thoracic disease · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGoal-directed therapy (GDT) can reduce postoperative complications in high-risk surgery patients. It is uncertain whether GDT has the same benefits in patients undergoing esophageal surgery. Goal of this Quality Improvement study was to evaluate the effects of a stroke volume guided GDT on post-operative outcome. METHODS AND
findingsWe compared the postoperative outcome of patients undergoing esophagectomy before (99 patients) and after (100 patients) implementation of GDT. There was no difference in the proportion of patients with a complication (56% vs. 54%, p = 0.82), hospital stay and mortality. The incidence of prolonged ICU stay (>48 hours) was reduced (28% vs. 12, p = .005) in patients treated with GDT. Secondary analysis of complication rate showed a decrease in pneumonia (29 vs. 15%, p = .02), mediastinal abscesses (12 vs. 3%, p = .02), and gastric tube necrosis (5% vs. 0%, p = .03) in patients treated with GDT. Patients in the GDT group received significantly less fluids but received more colloids.
conclusionsThe implementation of GDT during esophagectomy was not associated with reductions in overall morbidity, mortality and hospital length of stay. However, we observed a decrease in pneumonia, mediastinal abscesses, gastric tube necrosis, and ICU length of stay.
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