Evidence map›Paper›PMID 28253300›Full record

ArticlePloS one2017

The Pax gene family: Highlights from cephalopods.

Sandra Navet, Auxane Buresi, Sébastien Baratte, Aude Andouche, Laure Bonnaud-Ponticelli, Yann Bassaglia

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mobilizing molluscan models and genomes in biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
  6. The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. International journal of molecular sciences · 2018
    Article
  11. Article
  12. Review
  13. Article
  14. Eye Development inFrontiers in physiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sandra NavetUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Auxane BuresiUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Sébastien BaratteUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Aude AndoucheUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Laure Bonnaud-PonticelliUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.
Yann BassagliaUMR BOREA MNHN/CNRS7208/IRD207/UPMC/UCN/UA, Muséum National d'Histoire Naturelle, Sorbonne Universités, Paris, France.ORCID http://orcid.org/0000-0002-6627-7737
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pax genes play important roles in Metazoan development. Their evolution has been extensively studied but Lophotrochozoa are usually omitted. We addressed the question of Pax paralog diversity in Lophotrochozoa by a thorough review of available databases. The existence of six Pax families (Pax1/9, Pax2/5/8, Pax3/7, Pax4/6, Paxβ, PoxNeuro) was confirmed and the lophotrochozoan Paxβ subfamily was further characterized. Contrary to the pattern reported in chordates, the Pax2/5/8 family is devoid of homeodomain in Lophotrochozoa. Expression patterns of the three main pax classes (pax2/5/8, pax3/7, pax4/6) during Sepia officinalis development showed that Pax roles taken as ancestral and common in metazoans are modified in S. officinalis, most likely due to either the morphological specificities of cephalopods or to their direct development. Some expected expression patterns were missing (e.g. pax6 in the developing retina), and some expressions in unexpected tissues have been found (e.g. pax2/5/8 in dermal tissue and in gills). This study underlines the diversity and functional plasticity of Pax genes and illustrates the difficulty of using probable gene homology as strict indicator of homology between biological structures.

Indexed as

AnimalsCephalopodaPaired Box Transcription FactorsSequence AlignmentPaired Box Transcription Factors

Identifiers

PMID28253300
PMCPMC5333810
OpenAlexW2592146857

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.