ArticlePloS one2017
Clinical and neuroimaging characteristics of Chinese dementia with Lewy bodies.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuroimaging alterations in dementia with Lewy bodies and neuroimaging differences between dementia with Lewy bodies and Alzheimer's disease: An activation likelihood estimation meta-analysis.CNS neuroscience & therapeutics · 2022Pooled it
- Lewy body dementia: exploring biomarkers and pathogenic interactions of amyloid β, tau, and α-synuclein.Molecular neurodegeneration · 2025Review
- Blood-brain barrier breakdown in dementia with Lewy bodies.Fluids and barriers of the CNS · 2024Article
- Case report: Anti-ARHGAP26 autoantibodies in atypical dementia with Lewy bodies.Frontiers in dementia · 2023Article
- The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia.BMC neurology · 2022Article
- Association between prevalence rate of dementia with Lewy bodies and sleep characteristics in Chinese old adults.Frontiers in human neuroscience · 2022Article
- Association of Elevated Plasma Total Homocysteine With Dementia With Lewy Bodies: A Case-Control Study.Frontiers in aging neuroscience · 2021Article
- Tau PET and relative cerebral blood flow in dementia with Lewy bodies: A PET study.NeuroImage. Clinical · 2020Article
- Neuroimaging in Lewy body dementia.Journal of neurology · 2019Review
- Multi-modality molecular imaging characteristics of dementia with Lewy bodies.The Journal of international medical research · 2018Article
- Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies.Journal of neural transmission (Vienna, Austria : 1996) · 2018Review
- Cerebrospinal Fluid, Imaging, and Physiological Biomarkers in Dementia With Lewy Bodies.American journal of Alzheimer's disease and other dementiasReview
Corrections and comments
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Authors and funding
11 authors.
Funding
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Abstract
Dementia with Lewy bodies (DLB) is the second most common subtype of degenerative dementia. To our knowledge, available information about the clinical features of DLB in China remains limited. Our study therefore aimed to address this issue. Thirty-seven Chinese patients with probable DLB were recruited for this study. All subjects underwent neuropsychological assessment by trained neurologists, as well as undergoing MRI, 11C-PIB PET scans for Aβ deposition and 18F-FDG PET scans for regional cerebral glucose metabolism. Our results showed that the gender ratio of patients was 16:21 (F:M). The mean age of onset was 69.5 ± 9.0 years and the mean age at diagnosis was 71.8 ± 9.1 years. At diagnosis, the prevalence of three core clinical features of DLB was: 64.9% for fluctuating cognition, 73.0% for visual hallucinations and 62.2% for parkinsonism. The result from 11C-PiB PET and 18F-FDG PET scans confirmed Aβ deposition in the cortex and demonstrated hypometabolism in the bilateral temporoparietooccipital region, the frontal lobe, the insular lobe, and the posterior cingulate, precuneus and caudate nuclei. Our study elucidated the clinical features of Chinese DLB patients, and will improve the understanding and the early diagnosis of DLB in Chinese patients.
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