ArticlePLoS biology2017
Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature.
Article in PLoS biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 232 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
232 citing papers in PubMed, 16 syntheses or guidelines pooled it.
- The presence, clarity, and consistency of definitions in pregnancy outcomes in infertility trials: a systematic review.Human reproduction (Oxford, England) · 2025Pooled it
- A systematic review and meta-analysis of psychological treatments to improve sleep quality in university students.PloS one · 2025Pooled it
- Assessing the Evidential Value of Mental Fatigue and Exercise Research.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- The influence of journal submission guidelines on authors' reporting of statistics and use of open research practices: Five years later.Behavior research methods · 2023Pooled it
- Diffusion-Weighted Imaging in Mild Traumatic Brain Injury: A Systematic Review of the Literature.Neuropsychology review · 2023Pooled it
- Sleep deprivation and memory: Meta-analytic reviews of studies on sleep deprivation before and after learning.Psychological bulletin · 2021Pooled it
- Dyslexia treatment studies: A systematic review and suggestions on testing treatment efficacy with small effects and small samples.Behavior research methods · 2021Pooled it
- Sample size, sample size planning, and the impact of study context: systematic review and recommendations by the example of psychological depression treatment.Psychological medicine · 2021Pooled it
- Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.Brain imaging and behavior · 2021Pooled it
- Estimating publication bias in meta-analyses of peer-reviewed studies: A meta-meta-analysis across disciplines and journal tiers.Research synthesis methods · 2021Pooled it
- Is the Psychopathic Brain an Artifact of Coding Bias? A Systematic Review.Frontiers in psychology · 2021Pooled it
- Improving Reading Through Videogames and Digital Apps: A Systematic Review.Frontiers in psychology · 2021Pooled it
- Limited evidence for the effect of red color on cognitive performance: A meta-analysis.Psychonomic bulletin & review · 2020Pooled it
- The Potential of Functional Near-Infrared Spectroscopy-Based Neurofeedback-A Systematic Review and Recommendations for Best Practice.Frontiers in neuroscience · 2020Pooled it
- Pooled it
- Acetyl-L-carnitine for patients with hepatic encephalopathy.The Cochrane database of systematic reviews · 2019Pooled it
- Replicability of multivariate brain-behaviour associations depends on clinical profile.Communications biology · 2026Article
- Sample size calculation for training ensemble machine learning models on health data.Patterns (New York, N.Y.) · 2026Article
- A tutorial for calculating field-specific effect size distributions.Behavior research methods · 2026Article
- Expectation Modulates Hedonic Experiences and Midbrain Responses to Sweet Flavor.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
172 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have empirically assessed the distribution of published effect sizes and estimated power by analyzing 26,841 statistical records from 3,801 cognitive neuroscience and psychology papers published recently. The reported median effect size was D = 0.93 (interquartile range: 0.64-1.46) for nominally statistically significant results and D = 0.24 (0.11-0.42) for nonsignificant results. Median power to detect small, medium, and large effects was 0.12, 0.44, and 0.73, reflecting no improvement through the past half-century. This is so because sample sizes have remained small. Assuming similar true effect sizes in both disciplines, power was lower in cognitive neuroscience than in psychology. Journal impact factors negatively correlated with power. Assuming a realistic range of prior probabilities for null hypotheses, false report probability is likely to exceed 50% for the whole literature. In light of our findings, the recently reported low replication success in psychology is realistic, and worse performance may be expected for cognitive neuroscience.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.