ArticleEvolution; international journal of organic evolution2017
Genotype specificity among hosts, pathogens, and beneficial microbes influences the strength of symbiont-mediated protection.
Article in Evolution; international journal of organic evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 111 citations in OpenAlex.
- Phenotypic divergence is driven by mobile genetic elements in a heritable insect symbiont.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Host species-specific gene expression by a widespread and flexible chemosynthetic symbiont.The ISME journal · 2026Article
- Increasing Prevalence of Plant-Fungal Symbiosis Across Two Centuries of Environmental Change.Global change biology · 2025Article
- Cell surface Toll-like receptor polymorphisms influenceiScience · 2025Article
- Pathogen-microbiome interactions and the virulence of an entomopathogenic fungus.Applied and environmental microbiology · 2024Article
- Facultative symbiont virulence determines horizontal transmission rate without host specificity inEvolution letters · 2024Article
- Parasitoid species diversity has no effect on protective symbiont diversity in experimental host-parasitoid populations.Ecology and evolution · 2024Article
- Host-pathogen coevolution promotes the evolution of general, broad-spectrum resistance and reduces foreign pathogen spillover risk.Evolution letters · 2023Article
- Facultative symbiont virulence determines horizontal transmission rate without host strain specificity.bioRxiv : the preprint server for biology · 2023Article
- Specific resistance prevents the evolution of general resistance and facilitates disease emergence.Journal of evolutionary biology · 2023Article
- An aphid symbiont confers protection against a specialized RNA virus, another increases vulnerability to the same pathogen.Molecular ecology · 2023Article
- Aphid facultative symbionts confer no protection against the fungal entomopathogen Batkoa apiculata.PloS one · 2023Article
- Article
- Cereal Aphid Parasitoids in Europe (Hymenoptera: Braconidae: Aphidiinae): Taxonomy, Biodiversity, and Ecology.Insects · 2022Review
- Within-community variation of interspecific divergence patterns in passerine gut microbiota.Ecology and evolution · 2022Article
- Coevolution's conflicting role in the establishment of beneficial associations.Evolution; international journal of organic evolution · 2022Article
- Bottom-up effect of host protective symbionts on parasitoid diversity: Limited evidence from two field experiments.The Journal of animal ecology · 2022Article
- Similar cost ofEcology and evolution · 2022Article
- Frequent Drivers, Occasional Passengers: Signals of Symbiont-Driven Seasonal Adaptation and Hitchhiking in the Pea Aphid,Insects · 2021Article
- Genetic identity and genotype × genotype interactions between symbionts outweigh species level effects in an insect microbiome.The ISME journal · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The microbial symbionts of eukaryotes influence disease resistance in many host-parasite systems. Symbionts show substantial variation in both genotype and phenotype, but it is unclear how natural selection maintains this variation. It is also unknown whether variable symbiont genotypes show specificity with the genotypes of hosts or parasites in natural populations. Genotype by genotype interactions are a necessary condition for coevolution between interacting species. Uncovering the patterns of genetic specificity among hosts, symbionts, and parasites is therefore critical for determining the role that symbionts play in host-parasite coevolution. Here, we show that the strength of protection conferred against a fungal pathogen by a vertically transmitted symbiont of an aphid is influenced by both host-symbiont and symbiont-pathogen genotype by genotype interactions. Further, we show that certain symbiont phylogenetic clades have evolved to provide stronger protection against particular pathogen genotypes. However, we found no evidence of reciprocal adaptation of co-occurring host and symbiont lineages. Our results suggest that genetic variation among symbiont strains may be maintained by antagonistic coevolution with their host and/or their host's parasites.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.