Evidence map›Paper›PMID 28252578›Full record

ReviewNursing research

The Human Microbiome and Understanding the 16S rRNA Gene in Translational Nursing Science.

Nancy J Ames, Alexandra Ranucci, Brad Moriyama, Gwenyth R Wallen

Registry-linked trialAbstract readReview
In one paragraph

Review in Nursing research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05349227 (Comprehensive Outcomes for After Cancer Health), which is not on this map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05349227 narecruitingnot on this map

Comprehensive Outcomes for After Cancer Health (COACH): the Feasibility and Impact of an MHealth Augmented Coaching Program for Self-Management in Cancer Survivors

TypeinterventionalSponsorPack HealthRan2022 to 2027Enrolled625ConditionsOvarian Cancer, Breast Cancer, Lung Cancer, Gastric CancerArmsDigital Health Coaching Program, Fitbit
3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nancy J AmesNancy J. Ames, RN, PhD, is Clinical Nurse Scientist, Nursing Department, National Institutes of Health Clinical Center, Bethesda, Maryland. Alexandra Ranucci, BS, is MD/MPH Candidate, Tulane University School of Medicine, New Orleans, Louisiana. She was a Post-Baccalaureate Intramural Research Award Recipient, Nursing Department, National Institutes of Health Clinical Center, Bethesda, Maryland, at the time this paper was prepared. Brad Moriyama, PharmD, is Clinical Pharmacist, Pharmacy Department, National Institutes of Health Clinical Center, Bethesda, Maryland. Gwenyth R. Wallen, RN, PhD, is Chief Nurse Officer (Acting), Nursing Department, National Institutes of Health Clinical Center, Bethesda, Maryland.
Alexandra Ranucci
Brad Moriyama
Gwenyth R Wallen

Funding

A Description of the Oral Microbiome of Patients with Severe Aplastic AnemiaZIACL001191 · CLC · CLINICAL CENTER · PI AMES, NANCY J. · 2014 to 2019
$0k
Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

backgroundAs more is understood regarding the human microbiome, it is increasingly important for nurse scientists and healthcare practitioners to analyze these microbial communities and their role in health and disease. 16S rRNA sequencing is a key methodology in identifying these bacterial populations that has recently transitioned from use primarily in research to having increased utility in clinical settings.

objectivesThe objectives of this review are to (a) describe 16S rRNA sequencing and its role in answering research questions important to nursing science; (b) provide an overview of the oral, lung, and gut microbiomes and relevant research; and (c) identify future implications for microbiome research and 16S sequencing in translational nursing science. DISCUSSION: Sequencing using the 16S rRNA gene has revolutionized research and allowed scientists to easily and reliably characterize complex bacterial communities. This type of research has recently entered the clinical setting, one of the best examples involving the use of 16S sequencing to identify resistant pathogens, thereby improving the accuracy of bacterial identification in infection control. Clinical microbiota research and related requisite methods are of particular relevance to nurse scientists-individuals uniquely positioned to utilize these techniques in future studies in clinical settings.

Indexed as

Bacterial InfectionsHumansInfection ControlMicrobiotaNursing Methodology ResearchPolymerase Chain ReactionRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID28252578
PMCPMC5535273

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.