Evidence map›Paper›PMID 28252177›Full record

ArticleJournal of medical virology2017

Seroprevalence of Kaposi's sarcoma-associated herpesvirus among HIV-infected Uygurs in Xinjiang, China.

Zhenqiu Liu, Qiwen Fang, Sujuan Zhou, Veenu Minhas, Charles Wood, Na He, Tiejun Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of medical virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Zhenqiu LiuDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Qiwen FangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Sujuan ZhouDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Veenu MinhasNebraska Center of Virology and the School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Charles WoodNebraska Center of Virology and the School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
Na HeDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
Tiejun ZhangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai, China.ORCID 0000-0002-5187-7393
Fudan University · CNUniversity of Nebraska–Lincoln · US

Funding

KAPOSIS SARCOMA AND HUMAN HERPESVIRUS IN AFRICAR01CA075903 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 1998 to 2015
$11.1M
Supplement: Fogarty Training in HIV- and AIDS Associated Diseases/MalignanciesD43TW001429 · FIC · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2000 to 2015
$7.2M
EMORY AIDS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW001042 · FIC · EMORY UNIVERSITY · PI DEL RIO, CARLOS · 1998 to 2013
$6.8M
Seroprevalence of COVID-19 of cancer patients in TanzaniaU54CA190155 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI ANGELETTI, PETER C., SOLIMAN, AMR · 2014 to 2022
$4.5M
Zambia AIDS Malignancies Diagnosis and Pathogenesis Program SupplementU54CA221204 · NCI · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2017 to 2022
$3.8M
Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
FIC NIH HHS D43 TW001042FIC NIH HHS D43 TW001429NCI NIH HHS R01 CA075903NCI NIH HHS U54 CA190155NCI NIH HHS U54 CA221204NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), which primarily affects human immunodeficiency virus (HIV)-infected adults with advanced immunodeficiency. Xinjiang province in China is an endemic area for Kaposi's sarcoma (KS), however, currently, only limited data for KSHV infection among HIV-infected individuals living in this endemic area is available. A cross-sectional study of 86 HIV positive participants was conducted in Xinjiang, China from 2014 through 2015. Plasma samples were collected and screened for KSHV and HIV infection. HIV pol gene and KSHV ORF-K1 gene were amplified and sequenced, genotypes were determined by phylogenetic analysis. Over all, prevalence was 48.9% (42/86; 95%CI 38.4-59.3%) for KSHV. Only CRF07_BC subtype has been identified among all these HIV positive individuals, while the subtype A and C of KSHV were detected in the participants. Meanwhile, we found that those with high CD4 counts (>500) showed a lower anti-KSHV titer, compared with other groups. Our study indicated a high prevalence of KSHV among HIV positive individuals in Xinjiang, China. Thus, management of HIV/AIDS patients should include KSHV screen and should consider the risk of KSHV-associated malignancies.

Indexed as

AdultAntibodies, ViralChinaCross-Sectional StudiesEthnicityFemaleGenotypeGenotyping TechniquesHerpesviridae InfectionsHerpesvirus 8, HumanHIV-1HIV InfectionsHumansMaleMembrane ProteinsMiddle AgedAntibodies, ViralK1 protein, Human herpesvirus 8Membrane Proteinspol Gene Products, Human Immunodeficiency VirusViral Envelope ProteinsViral ProteinsChinaHIVKSHV

Identifiers

PMID28252177
PMCPMC9995688
OpenAlexW2591875775

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.